Evidence map›Paper›PMID 29279665›Full record

ArticleEuropean journal of dentistry

Modulating toll-like receptor-mediated inflammatory responses following exposure of whole cell and lipopolysaccharide component from

Sindy Cornelia Nelwan, Ricardo Adrian Nugraha, Anang Endaryanto, Indrawati Retno

Open access · hybridAbstract read
In one paragraph

Article in European journal of dentistry. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 45% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 9 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Sindy Cornelia NelwanDepartment of Pediatric Dentistry, Faculty of Dentistry, Universitas Airlangga, Surabaya, Indonesia.
Ricardo Adrian NugrahaDepartment of Medicine, Faculty of Medicine, Universitas Airlangga, Surabaya, Indonesia.
Anang EndaryantoDepartment of Child Health, Faculty of Medicine, Universitas Airlangga, Surabaya, Indonesia.
Indrawati RetnoDepartment of Oral Biology, Faculty of Dentistry, Universitas Airlangga, Surabaya, Indonesia.
Airlangga University · ID

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo explore host innate inflammatory response and the signal pathway induced by MATERIALS AND

methodsAnimal experimental study with pretest-posttest controlled group design were done between January 1 and December 10, 2016.. Total of 28 wistar rats had been used, randomized into 7 groups, each were given various dose of intra-sulcural injection of STATISTICAL ANALYSIS: Normality were measured by Shapiro-Wilk test, while statistical analysis made by ANOVA, t test, Pearson, and linear regression model..

resultsAt day 0, no significant difference TLR2 and TLR4 level were measured. At day 4, there is a slight difference between TLR2 and TLR4 level in each group. At day 11, there is a significant difference between TLR2 and TLR4 level in each group. Group with exposure of whole cell will develop greater TLR2 but lower TLR4 level. In the contrary, group with exposure of LPS will develop greater TLR4 but lower TLR2 level.

conclusionOur data supported that

Indexed as

Innate immunitylipopolysaccharidePorphyromonas gingivalistoll-like receptorwhole cell

Identifiers

PMID29279665
PMCPMC5727724
OpenAlexW2770884042

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.