Evidence map›Paper›PMID 29279414›Full record

ArticlePhysiological reports2017

T-tubule remodeling and increased heterogeneity of calcium release during the progression to heart failure in intact rat ventricle.

Jasleen K Singh, Varderes Barsegyan, Nikhil Bassi, William Marszalec, Shannon Tai, Shruthi Mothkur, Maaz Mulla, Elsa Nico, Yohannes Shiferaw, Gary L Aistrup and 1 more

Open access · goldAbstract read
In one paragraph

Article in Physiological reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.4field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 15 citations in OpenAlex.

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  11. Dyadic Plasticity in Cardiomyocytes.Frontiers in physiology · 2018
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Jasleen K SinghDepartment of Medicine (Cardiology), The Feinberg Cardiovascular Research Institute Northwestern University Feinberg School of Medicine, Chicago, Illinois.
Varderes BarsegyanDepartment of Physics and Astronomy, California State University, Northridge, California.
Nikhil BassiDepartment of Medicine (Cardiology), The Feinberg Cardiovascular Research Institute Northwestern University Feinberg School of Medicine, Chicago, Illinois.
William MarszalecDepartment of Medicine (Cardiology), The Feinberg Cardiovascular Research Institute Northwestern University Feinberg School of Medicine, Chicago, Illinois.
Shannon TaiDepartment of Medicine (Cardiology), The Feinberg Cardiovascular Research Institute Northwestern University Feinberg School of Medicine, Chicago, Illinois.
Shruthi MothkurDepartment of Medicine (Cardiology), The Feinberg Cardiovascular Research Institute Northwestern University Feinberg School of Medicine, Chicago, Illinois.
Maaz MullaDepartment of Medicine (Cardiology), The Feinberg Cardiovascular Research Institute Northwestern University Feinberg School of Medicine, Chicago, Illinois.
Elsa NicoDepartment of Medicine (Cardiology), The Feinberg Cardiovascular Research Institute Northwestern University Feinberg School of Medicine, Chicago, Illinois.
Yohannes ShiferawDepartment of Physics and Astronomy, California State University, Northridge, California.
Gary L AistrupDepartment of Medicine (Cardiology), The Feinberg Cardiovascular Research Institute Northwestern University Feinberg School of Medicine, Chicago, Illinois.
John Andrew WasserstromDepartment of Medicine (Cardiology), The Feinberg Cardiovascular Research Institute Northwestern University Feinberg School of Medicine, Chicago, Illinois ja-wasserstrom@northwestern.edu.
Northwestern University · USCalifornia State University, Northridge · US

Funding

Atrial arrhythmias and Ca2+ waves in HF: simulation and experimental studiesR01HL119095 · NHLBI · NORTHWESTERN UNIVERSITY AT CHICAGO · PI SHIFERAW, YOHANNES, WASSERSTROM, JOHN ANDREW · 2014 to 2018
$3.0M
NHLBI NIH HHS R01 HL119095NIH HHS R01-119095
6 · The paper itself

Abstract

A highly organized transverse-tubule (TT) system is essential to normal Ca

Indexed as

AnimalsCalciumCalcium SignalingDisease ProgressionHeart FailureHeart VentriclesMyocytes, CardiacRatsRats, Inbred SHRRats, Inbred WKYCalciumCa2+ releaseCa2+ transientsheart failurehypertensiontransverse tubules

Identifiers

PMID29279414
PMCPMC5742703
OpenAlexW2776096979

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.