Evidence map›Paper›PMID 29279041›Full record

ArticleRedox report : communications in free radical research2018

Exercise through a cardiac rehabilitation program attenuates oxidative stress in patients submitted to coronary artery bypass grafting.

José Francisco Taty Zau, Rodrigo Costa Zeferino, Nádia Sandrine Mota, Gerez Fernandes Martins, Salvador Manoel Serra, Therezil Bonates da Cunha, Daniel Medeiros Lima, Basilio de Bragança Pereira, Emília Matos do Nascimento, Danilo Wilhelm Filho and 2 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Redox report : communications in free radical research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.7field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 14 citations in OpenAlex.

  1. Review
  2. Hyperuricemia in Cardiac Rehabilitation Patients: Prevalence and Association with Functional Improvement and Left Ventricular Ejection Fraction.High blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension · 2024
    Article
  3. Pathophysiology and Management of Heart Failure in the Elderly.The International journal of angiology : official publication of the International College of Angiology, Inc · 2022
    Article
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 1 country.

José Francisco Taty Zaua Cardiology Department , University Hospital Clementino Fraga Filho , Rio de Janeiro , Brazil.ORCID http://orcid.org/0000-0002-1324-3381
Rodrigo Costa Zeferinoc Biochemistry Department, Laboratory of Experimental Biochemistry , Universidade Federal de Santa Catarina-UFSC , Florianópolis , Brazil.
Nádia Sandrine Motac Biochemistry Department, Laboratory of Experimental Biochemistry , Universidade Federal de Santa Catarina-UFSC , Florianópolis , Brazil.
Gerez Fernandes Martinsd Instituto Aloysio de Castro-IECAC, Universidade Estadual do Rio de Janeiro-UERJ , Rio de Janeiro , Brazil.
Salvador Manoel Serrad Instituto Aloysio de Castro-IECAC, Universidade Estadual do Rio de Janeiro-UERJ , Rio de Janeiro , Brazil.
Therezil Bonates da Cunhad Instituto Aloysio de Castro-IECAC, Universidade Estadual do Rio de Janeiro-UERJ , Rio de Janeiro , Brazil.
Daniel Medeiros Limad Instituto Aloysio de Castro-IECAC, Universidade Estadual do Rio de Janeiro-UERJ , Rio de Janeiro , Brazil.
Basilio de Bragança Pereiraa Cardiology Department , University Hospital Clementino Fraga Filho , Rio de Janeiro , Brazil.
Emília Matos do Nascimentoe Department of Biostatistics and Applied Statistics, Faculty of Medicine , Alberto Luiz Coimbra Institute of Graduate Studies and Research in Engineering, Universidade Federal do Rio de Janeiro-UFRJ , Rio de Janeiro , Brazil.ORCID http://orcid.org/0000-0001-8313-8766
Danilo Wilhelm Filhof Ecology and Zoology Department , Universidade Federal de Santa Catarina-UFSC , Florianópolis , Brazil.
Rozangela Curi Pedrosac Biochemistry Department, Laboratory of Experimental Biochemistry , Universidade Federal de Santa Catarina-UFSC , Florianópolis , Brazil.
Roberto Coury Pedrosaa Cardiology Department , University Hospital Clementino Fraga Filho , Rio de Janeiro , Brazil.
Universidade Federal do Rio de Janeiro · BRUniversidade do Estado do Rio de Janeiro · BRUniversidade Federal de Santa Catarina · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCardiovascular disease is the main cause of morbidity and mortality in the world and oxidative stress has been implicated in the pathogenesis. Cardiac rehabilitation in patients with coronary artery disease submitted to coronary artery bypass grafting may prevent cardiovascular events probably through the attenuation of oxidative stress. The aim of this study was to evaluate the benefits of a cardiac rehabilitation program in the control of the systemic oxidative stress.

methodsThe studied population consisted of 40 patients, with chronic stable coronary artery disease submitted to coronary artery bypass grafting, who attended a cardiac rehabilitation program. Biomarkers of oxidative stress were evaluated in the blood of these patients at different moments.

resultsAfter the onset of cardiac rehabilitation, there was a significant and progressive decrease in thiobarbituric acid reactive substances levels and protein carbonyls, an initial increase and subsequent decrease in superoxide dismutase, catalase and glutathione peroxidase activities. Also, a progressive increase of uric acid, while ferric reducing antioxidant power levels increased only at the end of the cardiac rehabilitation and a tendency to increase of glutathione contents.

conclusionsThe results suggest that regular exercise through a cardiac rehabilitation program can attenuate oxidative stress in chronic coronary artery disease patients submitted to coronary artery bypass grafting.

Indexed as

Coronary Artery BypassOxidative StressAdultAgedAntioxidantsBiomarkersCardiac RehabilitationCatalaseCoronary Artery DiseaseExerciseFemaleGlutathioneHumansMaleMiddle AgedSuperoxide DismutaseAntioxidantsBiomarkersCatalaseGlutathioneSuperoxide DismutaseThiobarbituric Acid Reactive Substancesantioxidants defensescardiac rehabilitation programCoronary artery diseasemyocardial revascularizationoxidative stress

Identifiers

PMID29279041
PMCPMC6748685
OpenAlexW2777835041

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.