Evidence map›Paper›PMID 29279024›Full record

ArticleJournal of toxicology and environmental health. Part A2018

Ultrafine particulate matter exposure impairs vasorelaxant response in superoxide dismutase 2-deficient murine aortic rings.

Jacqueline D Carter, Nageswara R Madamanchi, George A Stouffer, Marschall S Runge, Wayne E Cascio, Haiyan Tong

Erratum issuedAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of toxicology and environmental health. Part A, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors.

Jacqueline D Cartera Environmental Public Health Division , National Health and Environmental Effects Research Laboratory, US Environmental Protection Agency, Chapel Hill , NC , USA.
Nageswara R Madamanchib Department of Medicine , University of Michigan , Ann Arbor , MI , USA.
George A Stoufferc McAllister Heart Institute, Department of Medicine , University of North Carolina at Chapel Hill , Chapel Hill , NC , USA.
Marschall S Rungeb Department of Medicine , University of Michigan , Ann Arbor , MI , USA.
Wayne E Cascioa Environmental Public Health Division , National Health and Environmental Effects Research Laboratory, US Environmental Protection Agency, Chapel Hill , NC , USA.
Haiyan Tonga Environmental Public Health Division , National Health and Environmental Effects Research Laboratory, US Environmental Protection Agency, Chapel Hill , NC , USA.

Funding

OXIDATIVE STRESS AND VASCULAR AGINGP01AG024282 · NIA · UNIV OF NORTH CAROLINA CHAPEL HILL · PI CLEMMONS, DAVID ROBERT · 2004 to 2008
$7.4M
Molecular Characterization of NoxA1 in VSMC NADPH Oxidase ActivationR01HL111664 · NHLBI · UNIV OF NORTH CAROLINA CHAPEL HILL · PI RUNGE, MARSCHALL S. · 2012 to 2015
$1.5M
Intramural EPA EPA999999NHLBI NIH HHS R01 HL111664NIA NIH HHS P01 AG024282
6 · The paper itself

Abstract

Studies have linked exposure to ultrafine particulate matter (PM) and adverse cardiovascular events. PM-induced oxidative stress is believed to be a key mechanism underlying observed adverse vascular effects. Advanced age is one factor known to decrease antioxidant defenses and confer susceptibility to the detrimental vascular effects seen following PM exposure. The present study was designed to investigate the vasomotor responses following ultrafine PM exposure in wild type (WT) and superoxide dismutase 2-deficient (SOD2 ABBREVIATIONS: H

Indexed as

AgingAnimalsAortaAortic DiseasesMiceMice, Inbred C57BLParticulate MatterSuperoxide Dismutase-1Vasomotor SystemParticulate MatterSod1 protein, mouseSuperoxide Dismutase-1Aortasuperoxide dismutase (SOD)ultrafine PMvasoreactivity

Identifiers

PMID29279024
PMCPMC6136421

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.