Evidence map›Paper›PMID 29278360›Full record

ReviewMolecules (Basel, Switzerland)2017

A Concise Review of the Conflicting Roles of Dopamine-1 versus Dopamine-2 Receptors in Wound Healing.

Alexandra R Vaughn, Michael James Davis, Raja K Sivamani, Roslyn Rivkah Isseroff

Open access · goldAbstract readReview
In one paragraph

Review in Molecules (Basel, Switzerland), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.1field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 15 citations in OpenAlex.

  1. Review
  2. Histological Evaluation ofBiomedicines · 2026
    Article
  3. Article
  4. Review
  5. Article
  6. Review
  7. Review
  8. Article
  9. Catecholamines in the regulation of angiogenesis in cutaneous wound healing.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2020
    Review
  10. Biomolecules · 2020
    Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 4 institutions in 1 country.

Alexandra R VaughnDepartment of Dermatology, University of California-Davis, Sacramento, CA 95816, USA. arv42@drexel.edu.
Michael James DavisEmory University School of Medicine, Atlanta, GA 30307, USA. michael.james.davis@emory.edu.
Raja K SivamaniDepartment of Dermatology, University of California-Davis, Sacramento, CA 95816, USA. rksivamani@ucdavis.edu.
Roslyn Rivkah IsseroffDepartment of Dermatology, University of California-Davis, Sacramento, CA 95816, USA. rrisseroff@ucdavis.edu.
California State University, Sacramento · USEmory University · USUniversity of California, Davis · USVA Northern California Health Care System · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Catecholamines play an important regulatory role in cutaneous wound healing. The exact role of dopamine in human epidermis has yet to be fully elucidated. Current published evidence describes its differential effects on two separate families of G protein coupled receptors: D1-like and D2-like dopamine receptors. Dopamine may enhance angiogenesis and wound healing through its action on dopamine D1 receptors, while impairing wound healing when activating D2 receptors. This review summarizes the evidence for the role of dopamine in wound healing and describes potential mechanisms behind its action on D1 versus D2-like receptors in the skin.

Indexed as

AnimalsCell LineDopamineHumansReceptors, Dopamine D1Receptors, Dopamine D2Signal TransductionSkinWound HealingDopamineReceptors, Dopamine D1Receptors, Dopamine D2dopaminewound healingwounds

Identifiers

PMID29278360
PMCPMC5943953
OpenAlexW2776090105

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.