Evidence map›Paper›PMID 29277551›Full record

ArticleAnnals of epidemiology2018

Diabetes-related factors and abdominal aortic aneurysm events: the Atherosclerotic Risk in Communities Study.

Yasuhiko Kubota, Aaron R Folsom, James S Pankow, Lynne E Wagenknecht, Weihong Tang

Open access · greenAbstract read
In one paragraph

Article in Annals of epidemiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
1.2field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it, 21 citations in OpenAlex.

  1. Pooled it
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  5. Review
  6. Article
  7. Advanced Research of Abdominal Aortic Aneurysms on Metabolism.Frontiers in cardiovascular medicine · 2021
    Review
  8. Article
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Yasuhiko KubotaDivision of Epidemiology and Community Health, School of Public Health, University of Minnesota, Minneapolis. Electronic address: kubot007@umn.edu.
Aaron R FolsomDivision of Epidemiology and Community Health, School of Public Health, University of Minnesota, Minneapolis.
James S PankowDivision of Epidemiology and Community Health, School of Public Health, University of Minnesota, Minneapolis.
Lynne E WagenknechtDepartment of Epidemiology and Prevention, Wake Forest School of Medicine, Winston Salem, NC.
Weihong TangDivision of Epidemiology and Community Health, School of Public Health, University of Minnesota, Minneapolis.
University of Minnesota · USWake Forest University · US

Funding

Identifying Epidemiological Risk Factors for Abdominal Aortic AneurysmR01HL103695 · NHLBI · UNIVERSITY OF MINNESOTA · PI TANG, WEIHONG · 2011 to 2014
$2.3M
NHLBI NIH HHS HHSN268201100005CNHLBI NIH HHS HHSN268201100005GNHLBI NIH HHS HHSN268201100005INHLBI NIH HHS HHSN268201100006CNHLBI NIH HHS HHSN268201100007CNHLBI NIH HHS HHSN268201100007INHLBI NIH HHS HHSN268201100008CNHLBI NIH HHS HHSN268201100008INHLBI NIH HHS HHSN268201100009CNHLBI NIH HHS HHSN268201100009INHLBI NIH HHS HHSN268201100010CNHLBI NIH HHS HHSN268201100011CNHLBI NIH HHS HHSN268201100011INHLBI NIH HHS HHSN268201100012CNHLBI NIH HHS R01 HL103695
6 · The paper itself

Abstract

purposeTo test the hypothesis that diabetes-related factors (metabolic syndrome [MetS], glucose, insulin, and leptin) are inversely associated with abdominal aortic aneurysm (AAA) risk.

methodsWe followed 13,736 participants, aged 45-64 years, without prior AAA surgery at baseline (1987-1989), for AAA occurrence through 2011. Hazard ratios (HRs) and their 95% confidence intervals (CIs) of AAA were calculated using Cox regression.

resultsDuring 275,054 person-years of follow-up, we identified 518 AAA events. Fasting serum glucose was associated inversely with AAA risk (HR [95% CI] per one unit increment in log

conclusionsDiabetes, fasting glucose, and plasma leptin were inversely associated with risk of AAA. In contrast, the MetS was associated with increased risk of AAA, due to the influence of the non-glucose MetS components.

Indexed as

Aortic Aneurysm, AbdominalBlood GlucoseCholesterol, HDLDiabetes MellitusFemaleFollow-Up StudiesHumansHypertensionMaleMetabolic SyndromeMiddle AgedObesity, AbdominalBlood GlucoseCholesterol, HDLAbdominal aortic aneurysmDiabetesLeptinMetabolic syndrome

Identifiers

PMID29277551
PMCPMC5813832
OpenAlexW2774080185

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.