Trial reportAcademic pediatrics2018
Randomized Controlled Trial to Prevent Infant Overweight in a High-Risk Population.
Trial report in Academic pediatrics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 4 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
23 citing papers in PubMed, 4 syntheses or guidelines pooled it, 39 citations in OpenAlex.
- Effects of behavioural interventions for preventing obesity in young children from ethnic minority backgrounds: a systematic review of randomised controlled trials.Archives of public health = Archives belges de sante publique · 2026Pooled it
- The effectiveness of interventions during the first 1,000 days to improve energy balance-related behaviors or prevent overweight/obesity in children from socio-economically disadvantaged families of high-income countries: a systematic review.Obesity reviews : an official journal of the International Association for the Study of Obesity · 2023Pooled it
- Addressing obesity in the first 1000 days in high risk infants: Systematic review.Maternal & child nutrition · 2021Pooled it
- Interventions for supporting the initiation and continuation of breastfeeding among women who are overweight or obese.The Cochrane database of systematic reviews · 2019Pooled it
- Sleep-wake patterns in newborns are associated with infant rapid weight gain and incident adiposity in toddlerhood.Pediatric obesity · 2021Trial
- Home-based intervention for non-Hispanic black families finds no significant difference in infant size or growth: results from the Mothers & Others randomized controlled trial.BMC pediatrics · 2020Trial
- Calories, Caffeine and the Onset of Obesity in Young Children.Academic pediatrics · 2020Trial
- Evaluating the Baby-Act Behavioral Intervention Components: Participants' Compliance, Knowledge, Confidence, and Goals Set and Achieved.Academic pediatricsTrial
- A Multimethod Evaluation of the Futuros Fuertes Intervention to Promote Healthy Feeding, Screen Time, and Sleep Practices.Academic pediatricsTrial
- A Scoping Review of Instruments Used to Measure Weight and Body Composition in Infants Under 1 Year.Obesity reviews : an official journal of the International Association for the Study of Obesity · 2026Article
- Article
- A scoping review on the use of a participatory approach in interventions to combat overweight and obesity in low socioeconomic status communities.European journal of nutrition · 2025Article
- Associations of Infant Feeding, Sleep, and Weight Gain with the Toddler Gut Microbiome.Microorganisms · 2024Article
- Impact of an early 1000-day intervention for obesity prevention on adiposity and BMI at two years of age: A quasi-experimental study.Journal of global health · 2023Article
- African American mothers' perceptions of infant body size are prospectively associated with infant growth and BMI.American journal of human biology : the official journal of the Human Biology Council · 2023Article
- Trends in overweight and obesity in children under 24 months of age in Mexico (2012-2020): analysis of four national health surveys.Cadernos de saude publica · 2023Article
- Article
- Recruitment and retention of underrepresented and vulnerable populations to research.Public health nursing (Boston, Mass.) · 2021Article
- Factors affecting the growth of children till the age of three years with overweight whose mothers have diabetes mellitus: A population-based cohort study.BMC pediatrics · 2021Article
- Feasibility of a culturally adapted early childhood obesity prevention program among migrant mothers in Australia: a mixed methods evaluation.BMC public health · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 4 institutions in 1 country.
Funding
Abstract
objectivesInfants are at risk of overweight. Infant overweight predisposes child, adolescent, and adult to obesity. We hypothesized that parent education, initiated prenatally and provided in the home, would reduce the incidence of infant overweight at age 12 months.
methodsPregnant obese Latina women were recruited at Special Supplemental Nutrition Program for Women, Infants, and Children (WIC) and randomized to intervention versus control. Intervention subjects received home visits by trained Spanish-fluent community health workers who provided counseling on infant growth, breastfeeding, nutrition, child development, sleep, physical activity, and safety. Promotoras did not visit the control subjects. A research assistant collected outcome data on all subjects.
resultsCompared to controls, parent education did not reduce infant overweight. Infant overweight developed rapidly and was present in 46% of infants by age 6 months. Infants overweight at 6 months were likely to be overweight at age 12 months (r = 0.60, P < .0001). Overweight was more common in formula-fed infants at ages 6 months (P < .06) and 12 months (P = .005). Breastfeeding was less common in families with employed mothers (P = .02) and unemployed fathers (P < .01), but the father living with the mother at the time of the prenatal visit predicted successful breastfeeding at infant age 2 months (P < .003). Compared to formula feeding, overweight at age 12 months was 2.7 times less likely for infants breastfed for ≥2 months (P = .01).
conclusionsThe lack of success of the intervention may be explained in part by a high cesarean section rate in the intervention group, food and employment insecurity, and confounding by WIC breastfeeding promotion, which was available to all mothers. Breastfeeding was the most important mediator of infant overweight. The study supports efforts by WIC to vigorously promote breastfeeding.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.