Evidence map›Paper›PMID 29277420›Full record

ArticleInternational journal of biological macromolecules2018

Factors affecting the association of single- and double-stranded RNAs with montmorillonite nanoclays.

Archana Gujjari, Blanca V Rodriguez, Jorge Pescador, Corina Maeder, Gary W Beall, L Kevin Lewis

Open access · greenAbstract read
In one paragraph

Article in International journal of biological macromolecules, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.4field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 10 citations in OpenAlex.

  1. Self-Assembling Short Peptide Carriers for Gene Delivery.International journal of molecular sciences · 2026
    Review
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Archana GujjariChemistry and Biochemistry, Texas State University, 601 University Drive, San Marcos, TX, 78666, United States.
Blanca V RodriguezChemistry and Biochemistry, Texas State University, 601 University Drive, San Marcos, TX, 78666, United States.
Jorge PescadorChemistry and Biochemistry, Texas State University, 601 University Drive, San Marcos, TX, 78666, United States.
Corina MaederDepartment of Chemistry, Trinity University, One Trinity Place, San Antonio, TX, 78212, United States.
Gary W BeallChemistry and Biochemistry, Texas State University, 601 University Drive, San Marcos, TX, 78666, United States.
L Kevin LewisChemistry and Biochemistry, Texas State University, 601 University Drive, San Marcos, TX, 78666, United States. Electronic address: LL18@txstate.edu.
Texas State University · USTrinity University · US

Funding

South Texas Doctoral Bridge ProgramR25GM102783 · NIGMS · UNIVERSITY OF TEXAS HLTH SCIENCE CENTER · PI OYAJOBI, BABATUNDE OLUKAYODE, WHITTEN, STEVEN T · 2013 to 2022
$3.1M
NIGMS NIH HHS R25 GM102783
6 · The paper itself

Abstract

Montmorillonite (MMT) nanoclays exist as single and stacked sheet-like structures with large surface areas that can form stable associations with many naturally occurring biomolecules, including nucleic acids. They have been utilized successfully as vehicles for delivery of both drugs and genes into cells. Most previous studies have focused on interactions of MMT with DNA. In the current study, we have investigated the binding of small RNAs similar to those used for RNA interference (RNAi) therapy to two major forms of the clay, Na-MMT and Ca-MMT. Association of both forms of MMT with several double-stranded RNAs (dsRNAs), including 25mers, 54mers and cloverleaf-shaped transfer RNAs, was weak and increased only slightly after addition of Mg

Indexed as

Base SequenceBentoniteMagnesiumNanostructuresNucleic Acid ConformationRNA, Double-StrandedSodiumBentoniteMagnesiumRNA, Double-StrandedSodiumGene deliveryGene therapyNonviral vectorsRNA interferencesiRNA

Identifiers

PMID29277420
PMCPMC6247799
OpenAlexW2778773733

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.