ArticlePreventive medicine2018
Using path analysis to examine the relationship between sexual abuse in childhood and diabetes in adulthood in a sample of US adults.
Article in Preventive medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 2 of them syntheses that pooled it.
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Who cites it
14 citing papers in PubMed, 2 syntheses or guidelines pooled it, 25 citations in OpenAlex.
- Association of Adverse Childhood Experiences and Metabolic Syndrome: A Systematic Review and Meta-Analysis.Obesity reviews : an official journal of the International Association for the Study of Obesity · 2026Pooled it
- Sexual violence and cardiovascular disease risk: A systematic review and meta-analysis.Maturitas · 2021Pooled it
- A Double-Hit Model of Early-Life Stress and High-Fat Feeding Reveals Enhanced Exocrine Pancreatic Remodeling.Biology · 2026Article
- The relationship between pre-incarceration related social determinants and glycaemic control in African Americans with criminal legal involvement and type 2 diabetes.Diabetic medicine : a journal of the British Diabetic Association · 2026Article
- Trends in prevalence of adverse childhood experiences by sociodemographic factors in the United States: Behavioral Risk Factor Surveillance System 2009-2022.BMC public health · 2024Article
- Contextualizing risk, pathways, and solutions for the relationship between adverse childhood experiences (ACEs) and type 2 diabetes among inner-city African Americans: A qualitative analysis and development of a theoretical framework.Journal of affective disorders · 2024Article
- Article
- Relationship between social determinants of health and clinical outcomes in adults with type 2 diabetes in Lebanon.Journal of the National Medical Association · 2022Article
- Patterns of adverse childhood experiences and mental health outcomes among American Indians with type 2 diabetes.Child abuse & neglect · 2021Article
- The early effects of cumulative and individual adverse childhood experiences on child diet: Examining the role of socioeconomic status.Preventive medicine · 2021Article
- Relationship between adverse childhood experiences and perceived discrimination in adulthood.Journal of affective disorders · 2020Article
- Brain-gut-microbiome interactions in obesity and food addiction.Nature reviews. Gastroenterology & hepatology · 2020Review
- Adverse Childhood Experiences and Decreased Renal Function: Impact on All-Cause Mortality in U.S. Adults.American journal of preventive medicine · 2020Article
- The differential impact of adverse childhood experiences in the development of pre-diabetes in a longitudinal cohort of US adults.Journal of diabetes and its complications · 2018Article
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
Abstract
To understand mechanisms underlying the relationship between adverse childhood experiences (ACE) and diabetes the study evaluated mediators of the relationship between childhood sexual abuse and diabetes in adulthood. This study used cross-sectional data from the 2011 Behavioral Risk Factor Surveillance Survey (BRFSS). Participants totaled 48, 526 who completed the ACE module. Based on theoretical relationships, path analysis was used to investigate depression and obesity as pathways between childhood sexual abuse, and diabetes in adulthood. Among adults with diabetes, 11.6% experienced sexual abuse. In the unadjusted model without mediation, sexual abuse was significantly associated with depression (OR=4.48, CI 4.18-4.81), obesity (OR=1.28, CI 1.19-1.38), and diabetes (OR=1.39, CI 1.25-1.53). In the unadjusted model with mediation, depression and obesity were significantly associated with diabetes (OR=1.59, CI 1.48-1.72, and OR=3.77, CI 3.45-4.11, respectively), and sexual abuse and diabetes was no longer significant (OR=1.10, CI 0.98-1.23), suggesting full mediation. After adjusting for covariates in the mediation model, significance remained between sexual abuse and depression (OR=3.04, CI 2.80-3.29); sexual abuse and obesity (OR=1.41, CI 1.29-1.53), depression and diabetes (OR=1.35, CI 1.23-1.47); and obesity and diabetes (OR=3.53, CI 3.20-3.90). The relationship between sexual abuse and diabetes remained insignificant (OR=1.09, CI 0.96-1.24). This study demonstrates that depression and obesity are significant pathways through which childhood sexual abuse may be linked to diabetes in adulthood. These results can guide intervention development, including multifaceted approaches to treat depression and increase physical activity in patients with a history of sexual abuse to prevent diabetes.
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