ArticleContemporary clinical trials2018
The Flexible Lifestyle Empowering Change (FLEX) intervention for self-management in adolescents with type 1 diabetes: Trial design and baseline characteristics.
Article in Contemporary clinical trials, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05147324 (Individualized Planned Eating Patterns to Improve Glycemic Management in Adolescents With Type 1 Diabetes), which is not on this map. Cited by 18 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Individualized Planned Eating Patterns to Improve Glycemic Management in Adolescents With Type 1 Diabetes: A Pilot Clinical Trial
Who cites it
18 citing papers in PubMed.
- A High Protein Diet Is Associated with Improved Glycemic Control Following Exercise among Adolescents with Type 1 Diabetes.Nutrients · 2023Trial
- More hypoglycemia not associated with increasing estimated adiposity in youth with type 1 diabetes.Pediatric research · 2023Trial
- Mindfulness, disordered eating, and impulsivity in relation to glycemia among adolescents with type 1 diabetes and suboptimal glycemia from the Flexible Lifestyles Empowering Change (FLEX) intervention trial.Pediatric diabetes · 2022Trial
- Identification of clinically relevant dysglycemia phenotypes based on continuous glucose monitoring data from youth with type 1 diabetes and elevated hemoglobin A1c.Pediatric diabetes · 2019Trial
- Assessment of a Precision Medicine Analysis of a Behavioral Counseling Strategy to Improve Adherence to Diabetes Self-management Among Youth: A Post Hoc Analysis of the FLEX Trial.JAMA network open · 2019Trial
- Dysglycemia among youth with type 1 diabetes and suboptimal glycemic control in the Flexible Lifestyle Empowering Change trial.Pediatric diabetes · 2019Trial
- Efficacy of the Flexible Lifestyles Empowering Change intervention on metabolic and psychosocial outcomes in adolescents with type 1 diabetes (FLEX): a randomised controlled trial.The Lancet. Child & adolescent health · 2018Trial
- Review of Health Care Professional-Delivered Behavioral Interventions for Youth with Type 1 Diabetes.Current diabetes reports · 2025Review
- Pre-exercise protein intake is associated with reduced time in hypoglycaemia among adolescents with type 1 diabetes.Diabetes, obesity & metabolism · 2024Article
- Eating behaviors and estimated body fat percentage among adolescents with type 1 diabetes.Diabetes research and clinical practice · 2024Article
- Transition to self-management among emerging adults with type 1 diabetes: a mixed methods study.Frontiers in clinical diabetes and healthcare · 2024Article
- A randomized controlled clinical trial to improve health outcomes in youth with type 1 diabetes: Study design and baseline characteristics.Contemporary clinical trials · 2023Article
- What Are the Various Comprehensive Treatment Models to Improve Self-Efficacy and Self-Management in Adolescents with Diabetes Mellitus? A Scoping Review.Iranian journal of public health · 2023Article
- Review
- Design of the Advancing Care for Type 1 Diabetes and Obesity Network energy metabolism and sequential multiple assignment randomized trial nutrition pilot studies: An integrated approach to develop weight management solutions for individuals with type 1 diabetes.Contemporary clinical trials · 2022Article
- Characterization of youth goal setting in the self-management of type 1 diabetes and associations with HbA1c: The Flexible Lifestyle Empowering Change trial.Pediatric diabetes · 2020Article
- Understanding adolescent and parent acceptability and feasibility experience in a large Type 1 diabetes mellitus behavioural trial.Diabetic medicine : a journal of the British Diabetic Association · 2020Article
- Two-step recruitment process optimizes retention in FLEX clinical trial.Contemporary clinical trials communications · 2018Article
Corrections and comments
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Authors and funding
9 authors.
Funding
Abstract
The Flexible Lifestyle Empowering Change (FLEX) Intervention Study is a multi-site randomized controlled trial to test the efficacy of an adaptive behavioral intervention to promote self-management for youth with type 1 diabetes mellitus (T1D). This paper details FLEX design, demographic characteristics of the sample, and outcome variables at baseline. Participants were randomized to either an intervention or control arm after their baseline standardized measurement visit. Baseline data for the primary (glycemic levels) and secondary outcome variables (e.g., motivation and problem-solving, health-related quality of life, risk factors associated with T1D complications) as well as the potential mediator variables (e.g., self-management behavior, family conflict and responsibility) suggest that the study sample was representative of the general population of adolescents with T1D and their parents. The FLEX adaptive intervention is an innovative application of a tailored treatment intervention designed to be readily adopted in real-world practice to meet each adolescent's individualized T1D self-management goals.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.