Evidence map›Paper›PMID 29277284›Full record

ArticleAlcohol (Fayetteville, N.Y.)2018

Alcohol withdrawal upregulates mRNA encoding for Ca

Jamila Newton, Shubhankar Suman, Luli R Akinfiresoye, Kamal Datta, David M Lovinger, Prosper N'Gouemo

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Alcohol (Fayetteville, N.Y.), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.2field-weighted citation impact, top 43% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Article
  3. The Inferior Colliculus in Alcoholism and Beyond.Frontiers in systems neuroscience · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Jamila NewtonGeorgetown University Medical Center, Department of Pediatrics, Washington D.C., USA.
Shubhankar SumanGeorgetown University Medical Center, Department of Biochemistry and Molecular & Cellular Biology, Washington D.C., USA.
Luli R AkinfiresoyeGeorgetown University Medical Center, Department of Pediatrics, Washington D.C., USA.
Kamal DattaGeorgetown University Medical Center, Department of Biochemistry and Molecular & Cellular Biology, Washington D.C., USA.
David M LovingerLaboratory for Integrative Neuroscience, National Institute on Alcohol Abuse and Alcoholism, Rockville, MD, USA.
Prosper N'GouemoGeorgetown University Medical Center, Department of Pediatrics, Washington D.C., USA. Electronic address: pn@georgetown.edu.
Georgetown University Medical Center · USGeorgetown University · USNational Institute on Alcohol Abuse and Alcoholism · US

Funding

Synaptic Transmission: Modulation, Plasticity And Effects Of Drugs Of AbuseZIAAA000407 · NIAAA · NATIONAL INSTITUTE ON ALCOHOL ABUSE AND ALCOHOLISM · PI LOVINGER, DAVID M · 2009 to 2025
$29.6M
Corticostriatal mechanisms of action learning and habit formationZIAAA000416 · NIAAA · NATIONAL INSTITUTE ON ALCOHOL ABUSE AND ALCOHOLISM · PI LOVINGER, DAVID M · 2009 to 2025
$25.2M
Synaptic Transmission: Modulation, Plasticity And Effects Of Drugs Of AbuseZ01AA000407 · NIAAA · NATIONAL INSTITUTE ON ALCOHOL ABUSE AND ALCOHOLISM · PI LOVINGER, DAVID M · 2002 to 2008
$3.6M
Mechanisms of Alcohol Withdrawal Seizures: Role of L-type Ca2+ ChannelsR01AA020073 · NIAAA · GEORGETOWN UNIVERSITY · PI N'GOUEMO, PROSPER · 2011 to 2015
$1.7M
Intramural NIH HHS Z01 AA000407NIAAA NIH HHS R01 AA020073NIAAA NIH HHS ZIA AA000407
6 · The paper itself

Abstract

We previously reported increased current density through P-type voltage-gated Ca

Indexed as

EthanolAlcohol Withdrawal SeizuresAnimalsCalcium Channels, N-TypeDisease Models, AnimalInferior ColliculiMaleMembrane PotentialsNeuronsRats, Sprague-DawleyRNA, MessengerTime FactorsUp-RegulationCalcium Channels, N-TypeEthanolRNA, MessengerAudiogenic seizuresCacna1aP/Q-type calcium channel

Identifiers

PMID29277284
PMCPMC6939454
OpenAlexW2759390765

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.