Evidence map›Paper›PMID 29277142›Full record

Observational studyThe Libyan journal of medicine2018

Carriage of multidrug-resistant bacteria among pediatric patients before and during their hospitalization in a tertiary pediatric unit in Tunisia.

Miniar Tfifha, Asma Ferjani, Manel Mallouli, Nesrine Mlika, Saoussen Abroug, Jalel Boukadida

Open access · goldAbstract readObservational Study
In one paragraph

Observational study in The Libyan journal of medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
0.6field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it, 29 citations in OpenAlex.

  1. Pooled it
  2. Article
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  7. Clonal Spread of Hospital-Acquired NDM-1-ProducingAntibiotics (Basel, Switzerland) · 2023
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  8. Article
  9. Rate of Multidrug-resistance to Antimicrobial Drugs in Patients in Pediatric Neurointensive Care.Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Miniar Tfifhaa Pediatric Department, Sahloul Hospital, UR02SP13 , CHU Farhat Hached , Sousse , Tunisia.
Asma Ferjanib Microbiology and Immunology Department, UR02SP13 , CHU Farhat Hached , Sousse , Tunisia.
Manel Malloulic Faculty of Medicine , University of Sousse , Sousse , Tunisia.
Nesrine Mlikad Pediatric Department , Sahloul Hospital , Sousse , Tunisia.ORCID http://orcid.org/0000-0002-9365-0605
Saoussen Abrougd Pediatric Department , Sahloul Hospital , Sousse , Tunisia.
Jalel Boukadidab Microbiology and Immunology Department, UR02SP13 , CHU Farhat Hached , Sousse , Tunisia.
Hôpital Sahloul · TNHôpital Farhat Hached · TNUniversity of Sousse · TN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The pandemic spread of multidrug-resistant (MDR) bacteria (i.e., methicillin-resistant Staphylococcus aureus (MRSA), extended-spectrum b-lactamase-producing Enterobacteriaceae (ESBLPE), vancomycin-resistant enterococci, carbapenemase-producing Enterobacteriaceae (CPE), multiresistant Pseudomonas aeruginosa and multiresistant Acinetobacter baumannii) pose a threat to healthcare Worldwide. We found limited data of MDR bacteria in pediatric patients hospitalized in Tunisian tertiary healthcare.The aim of the study is to evaluate the acquisition rate of MDR acquisition during hospitalization and to explore some of the associated risk factors for both carriage and acquisition at the pediatric department, Sahloul University Hospital. During September and October 2016, newly admitted patients were screened, at admission, during care and at discharge. Risk factors for colonization were explored by multivariate analysis. Of 112 newly admitted patients, 8.92% were colonized with at least one MDR. No risk factor was identified at admission. During hospitalization, five newly acquisition MDR (4.9%) were detected and eight (7.84%) at discharge. The specie most frequently detected on admission was Escherichia coli (50%), whereas, on discharge, Escherichia coli and K. pneumoniae were the species most frequently detected (52.7%). The pediatric intensive care unit (PICU) hospitalization, the length of hospital stay (more than 3days) and age under 2 years were identified as risk factor for acquisition of MDR during hospitalization. We identified several independent risk factors for contracting MDR bacteria during hospitalization in a tertiary pediatric department. The incidence of symptomatic MDR Infection among those colonized should be under close surveillance and long-term screening for those children is required. An institutional screening program for MDR especially in PICU might be discussed in regards to cost effectiveness.

Indexed as

Age FactorsCarrier StateChild, PreschoolCross InfectionDrug Resistance, Multiple, BacterialEscherichia coliFemaleHumansIntensive Care Units, PediatricKlebsiella pneumoniaeLength of StayMaleNosePatient AdmissionPatient DischargePrevalenceChildrencolonizationhospitalizationmultidrug resistance

Identifiers

PMID29277142
PMCPMC5757224
OpenAlexW2777528221

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.