Evidence map›Paper›PMID 29276819›Full record

ArticleChembiochem : a European journal of chemical biology2018

Stabilization of the Reductase Domain in the Catalytically Self-Sufficient Cytochrome P450

Gloria Saab-Rincón, Hanan Alwaseem, Valeria Guzmán-Luna, Leticia Olvera, Rudi Fasan

Abstract read
In one paragraph

Article in Chembiochem : a European journal of chemical biology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
2.2field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 23 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Gloria Saab-RincónDepartamento de Ingeniería Celular y Biocatálisis, Instituto de Biotecnología, Universidad Nacional Autónoma de México, Apdo. Postal 510-3, 62250, Cuernavaca, Mor., México.ORCID 0000-0002-5251-1000
Hanan AlwaseemDepartment of Chemistry, University of Rochester, 120 Trustee Road, Rochester, NY, 14627, USA.ORCID 0000-0002-4946-1436
Valeria Guzmán-LunaDepartamento de Ingeniería Celular y Biocatálisis, Instituto de Biotecnología, Universidad Nacional Autónoma de México, Apdo. Postal 510-3, 62250, Cuernavaca, Mor., México.ORCID 0000-0002-2242-5953
Leticia OlveraDepartamento de Ingeniería Celular y Biocatálisis, Instituto de Biotecnología, Universidad Nacional Autónoma de México, Apdo. Postal 510-3, 62250, Cuernavaca, Mor., México.
Rudi FasanDepartment of Chemistry, University of Rochester, 120 Trustee Road, Rochester, NY, 14627, USA.ORCID 0000-0003-4636-9578
Universidad Nacional Autónoma de México · MXUniversity of Rochester · US

Funding

Selective P450 Oxidation Catalysts for Synthesis of Bioactive MoleculesR01GM098628 · NIGMS · UNIVERSITY OF TEXAS DALLAS · PI FASAN, RUDI · 2012 to 2024
$4.7M
NIGMS NIH HHS R01 GM098628
6 · The paper itself

Abstract

The multidomain, catalytically self-sufficient cytochrome P450 BM-3 from Bacillus megaterium (P450

Indexed as

Bacillus megateriumBiocatalysisCytochrome P-450 Enzyme SystemEnzyme StabilityModels, MolecularMutagenesis, Site-DirectedOxidoreductasesProtein DomainsTemperatureCytochrome P-450 Enzyme SystemOxidoreductasesconsensus mutagenesisCYP102A1cytochrome P450enzyme thermostabilizationP450 BM-3

Identifiers

PMID29276819
PMCPMC5941085
OpenAlexW2780676462

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.