ArticleUltrasound international open2017
Comparison of Tissue Stiffness Using Shear Wave Elastography in Men with Normal Testicular Tissue, Testicular Microlithiasis and Testicular Cancer.
Article in Ultrasound international open, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed, 31 citations in OpenAlex.
- Modern diagnostics: ultrasound elastography and magnetic resonance imaging in initial evaluation of testicular cancer.The Canadian journal of urology · 2025Article
- Testicular Two-Dimensional Shear Wave Elastography, Peak Systolic Velocity, Volume and Epididymal Thickness: Establishment of Normal Reference Values and Discrimination From Orchitis in Adult Patients Presenting With Acute Scrotal Pain.Australasian journal of ultrasound in medicine · 2025Article
- Mechanical signal-mediated mitochondria-endoplasmic reticulum contacts modulate Leydig cell testosterone biosynthesis during testis development.Molecular human reproduction · 2025Article
- A review of multiparametric ultrasound imaging in the clinical setting: scrotal contents.Abdominal radiology (New York) · 2025Review
- Comparison Between Strain and 2D Shear Wave Elastography of Testes in Healthy Dogs.Animals : an open access journal from MDPI · 2025Article
- Elastography of the Male Pelvic Region-Perspectives on Malignant Lesions.Diagnostics (Basel, Switzerland) · 2024Review
- Imaging Techniques to Differentiate Benign Testicular Masses from Germ Cell Tumors.Current urology reports · 2023Review
- Testicular Evaluation Using Shear Wave Elastography (SWE) in Patients with Varicocele.Journal of imaging · 2023Article
- Sonoelastography for Testicular Tumor Identification: A Systematic Review and Meta-Analysis of Diagnostic Test Accuracy.Cancers · 2023Review
- Ultrasound and Magnetic Resonance Imaging of Burned-Out Testicular Tumours: The Diagnostic Keys Based on 48 Cases.Cancers · 2022Article
- Elastography in the Urological Practice: Urinary and Male Genital Tract, Prostate Excluded-Review.Diagnostics (Basel, Switzerland) · 2022Review
- Application of real-time shear wave elastography in the assessment of male infertility.Quantitative imaging in medicine and surgery · 2022Article
- Contemporary options and future perspectives: three examples highlighting the challenges in testicular cancer imaging.World journal of urology · 2022Review
- Causal contributors to tissue stiffness and clinical relevance in urology.Communications biology · 2021Review
- 3D Printing Improved Testicular Prostheses: Using Lattice Infill Structure to Modify Mechanical Properties.Frontiers in surgery · 2021Article
- Elastography of focal testicular lesions: current concepts and utility.Ultrasonography (Seoul, Korea) · 2019Article
Corrections and comments
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Authors and funding
6 authors at 3 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesTo compare elastography measurements in men with normal testicular tissue, testicular microlithiasis and testicular cancer.
methodsA total of 248 consecutive patients were included. All men provided written informed consent. Testicular stiffness was assessed using shear wave elastography (SWE). Three SWE velocity measurements were assessed in each testicle. The patients were divided into three groups; men with normal testicular tissue (n=130), men with testicular microlithiasis (n=99) and men with testicular cancer (n=19).
resultsWe found a higher mean velocity in the group of patients with testicular cancer (1.92 m/s (95% CI 1.82-2.03)) compared to both the group with normal tissue (0.76 m/s (95% CI: 0.75-0.78)) (p<0.001) and the group with testicular microlithiasis 0.79 m/s (95% CI: 0.77-0.81) (p<0.001).
conclusionThe presence of testicular microlithiasis increased stiffness slightly, but within the range of variation in normal testicles. Increased stiffness may indicate testicular malignancy in testicular lesions. Ultrasound elastography could be a very useful tool when investigating scrotum.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.