Evidence map›Paper›PMID 29276798›Full record

ArticleIEEE transactions on radiation and plasma medical sciences2017

A Time-Walk Correction Method for PET Detectors Based on Leading Edge Discriminators.

Junwei Du, Jeffrey P Schmall, Martin S Judenhofer, Kun Di, Yongfeng Yang, Simon R Cherry

Abstract read
In one paragraph

Article in IEEE transactions on radiation and plasma medical sciences, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Article
  2. Article
  3. A Time-Walk and Timing-Shift Correction Method for Dual-Ended Readout TOF-DOI PET Detectors.IEEE transactions on radiation and plasma medical sciences · 2025
    Article
  4. Development of Whole-Body TOF-DOI PET Detector Using Dual-Ended Readout Method.IEEE transactions on instrumentation and measurement · 2025
    Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Junwei DuDepartment of Biomedical Engineering, University of California, Davis, CA 95616 USA.
Jeffrey P SchmallDepartment of Biomedical Engineering, University of California.
Martin S JudenhoferDepartment of Biomedical Engineering, University of California, Davis, CA 95616 USA.
Kun DiDepartment of Biomedical Engineering, University of California, Davis, CA 95616 USA.
Yongfeng YangDepartment of Biomedical Engineering, University of California, Davis, CA 95616 USA.
Simon R CherryDepartment of Biomedical Engineering, University of California, Davis, CA 95616 USA.

Funding

National Institute on Aging (NIA) ColonyP51OD011107 · OD · UNIVERSITY OF CALIFORNIA AT DAVIS · PI Simon J. Atkinson · 2012 to 2026
$191.5M
Innovative Silicon Photomultiplier Technologies for Small-Animal PETR01EB019439 · NIBIB · UNIVERSITY OF CALIFORNIA AT DAVIS · PI CHERRY, SIMON R · 2015 to 2018
$1.4M
NIBIB NIH HHS R01 EB019439NIH HHS P51 OD011107
6 · The paper itself

Abstract

The leading edge timing pick-off technique is the simplest timing extraction method for PET detectors. Due to the inherent time-walk of the leading edge technique, corrections should be made to improve timing resolution, especially for time-of-flight PET. Time-walk correction can be done by utilizing the relationship between the threshold crossing time and the event energy on an event by event basis. In this paper, a time-walk correction method is proposed and evaluated using timing information from two identical detectors both using leading edge discriminators. This differs from other techniques that use an external dedicated reference detector, such as a fast PMT-based detector using constant fraction techniques to pick-off timing information. In our proposed method, one detector was used as reference detector to correct the time-walk of the other detector. Time-walk in the reference detector was minimized by using events within a small energy window (508.5 - 513.5 keV). To validate this method, a coincidence detector pair was assembled using two SensL MicroFB SiPMs and two 2.5 mm × 2.5 mm × 20 mm polished LYSO crystals. Coincidence timing resolutions using different time pick-off techniques were obtained at a bias voltage of 27.5 V and a fixed temperature of 20 °C. The coincidence timing resolution without time-walk correction were 389.0 ± 12.0 ps (425 -650 keV energy window) and 670.2 ± 16.2 ps (250-750 keV energy window). The timing resolution with time-walk correction improved to 367.3 ± 0.5 ps (425 - 650 keV) and 413.7 ± 0.9 ps (250 - 750 keV). For comparison, timing resolutions were 442.8 ± 12.8 ps (425 - 650 keV) and 476.0 ± 13.0 ps (250 - 750 keV) using constant fraction techniques, and 367.3 ± 0.4 ps (425 - 650 keV) and 413.4 ± 0.9 ps (250 - 750 keV) using a reference detector based on the constant fraction technique. These results show that the proposed leading edge based time-walk correction method works well. Timing resolution obtained using this method was equivalent to that obtained using a reference detector and was better than that obtained using constant fraction discriminators.

Indexed as

Leading edge discriminatorPETTime of FlightTime-walk correctionTiming resolution

Identifiers

PMID29276798
PMCPMC5739333

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.