ArticleNutrition and healthy aging2017
Effect of alternate day fasting on markers of bone metabolism: An exploratory analysis of a 6-month randomized controlled trial.
Article in Nutrition and healthy aging, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 8 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
27 citing papers in PubMed, 8 syntheses or guidelines pooled it, 42 citations in OpenAlex.
- Effects of macro- and micronutrient intake on bone mineral density, osteoporotic fracture risk, inflammation, and functional rehabilitation outcomes in orthopedic patients: a systematic review and meta-analysis.Frontiers in nutrition · 2026Pooled it
- Effects of different types of intermittent fasting on metabolic outcomes: an umbrella review and network meta-analysis.BMC medicine · 2024Pooled it
- Pooled it
- Intermittent Energy Restriction for Weight Loss: A Systematic Review of Cardiometabolic, Inflammatory and Appetite Outcomes.Biological research for nursing · 2022Pooled it
- Effect of Carbohydrate-Restricted Diets and Intermittent Fasting on Obesity, Type 2 Diabetes Mellitus, and Hypertension Management: Consensus Statement of the Korean Society for the Study of Obesity, Korean Diabetes Association, and Korean Society of Hypertension.Diabetes & metabolism journal · 2022Pooled it
- Intermittent fasting for the prevention of cardiovascular disease.The Cochrane database of systematic reviews · 2021Pooled it
- The Influence of Fasting and Energy Restricting Diets on Blood Pressure in Humans: A Systematic Review and Meta-Analysis.High blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension · 2020Pooled it
- Health Effects of Alternate-Day Fasting in Adults: A Systematic Review and Meta-Analysis.Frontiers in nutrition · 2020Pooled it
- Trial
- The effects of time-restricted eating and weight loss on bone metabolism and health: a 6-month randomized controlled trial.Obesity (Silver Spring, Md.) · 2023Trial
- Time-Restricted Eating for 12 Weeks Does Not Adversely Alter Bone Turnover in Overweight Adults.Nutrients · 2021Trial
- Severely restricting energy intake for 24 h does not affect markers of bone metabolism at rest or in response to re-feeding.European journal of nutrition · 2020Trial
- Sex-Specific Responses to Intermittent Fasting: A Narrative Review Across Physiological, Clinical, and Psychosocial Contexts.Nutrients · 2026Review
- The impact of intermittent energy restriction on women's health.The Proceedings of the Nutrition Society · 2026Review
- Weight loss induced bone loss: mechanism of action and clinical implications.Bone research · 2025Review
- Effects of Short-Term (20-Day) Alternate-Day Modified Fasting and Time-Restricted Feeding on Fasting Glucose and IGF-1 in Obese Young Women.Diseases (Basel, Switzerland) · 2025Article
- The Effects of Different Dietary Patterns on Bone Health.Nutrients · 2024Review
- Ramadan fasting and exercise combination therapy: A novel approach for osteoporosis prevention in ovariectomized rats.Frontiers in physiology · 2024Article
- Intermittent fasting and bone health: a bone of contention?The British journal of nutrition · 2023Review
- Effect of Carbohydrate-Restricted Diets and Intermittent Fasting on Obesity, Type 2 Diabetes Mellitus, and Hypertension Management: Consensus Statement of the Korean Society for the Study of Obesity, Korean Diabetes Association, and Korean Society of Hypertension.Journal of obesity & metabolic syndrome · 2022Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors at 4 institutions in 1 country.
Funding
Abstract
backgroundAlternate day fasting (ADF) is a novel diet therapy that reduces body weight, but its effect on bone health remains unknown.
objectiveThis study examined the impact of ADF versus traditional daily calorie restriction (CR) on markers of bone metabolism in a 6-month randomized controlled trial.
methodsOverweight and obese subjects (
resultsBody weight decreased similarly (
conclusionThese findings suggest that 6 months of ADF does not have any deleterious impact on markers of bone metabolism in obese adults with moderate weight loss.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.