Evidence map›Paper›PMID 29276782›Full record

ArticleCancer translational medicine2017

Stemness-Related Markers in Cancer.

Wenxiu Zhao, Yvonne Li, Xun Zhang

Open access · greenAbstract read
In one paragraph

Article in Cancer translational medicine, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 139 papers.

0numbers the graph read from it
0cells of the map it votes in
139citing papers in PubMed
4.7field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

139 citing papers in PubMed, 261 citations in OpenAlex.

  1. Article
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  8. Stemness reducible effects of glyasperin A against NCCIT teratocarcinomas.Naunyn-Schmiedeberg's archives of pharmacology · 2025
    Article
  9. Article
  10. Review
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  12. Review
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  15. MiRNAs: main players of cancer drug resistance target ABC transporters.Naunyn-Schmiedeberg's archives of pharmacology · 2025
    Review
  16. Advanced drug delivery platforms target cancer stem cells.Asian journal of pharmaceutical sciences · 2025
    Review
  17. Article
  18. Article
  19. Article
  20. CD24 flags anastasis in melanoma cells.Apoptosis : an international journal on programmed cell death · 2025
    Article

79 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Wenxiu ZhaoNeuroendocrine Unit, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts 02114.
Yvonne LiDana Farber cancer Institute and Harvard Medical School, Boston, Massachusetts 02115.
Xun ZhangNeuroendocrine Unit, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts 02114.
Harvard University · US

Funding

The Role of lncRNA MEG3 in Clinically Non-functioning Pituitary AdenomasR01CA193520 · NCI · MASSACHUSETTS GENERAL HOSPITAL · PI SOBERMAN, ROY · 2016 to 2020
$1.9M
NCI NIH HHS R01 CA193520
6 · The paper itself

Abstract

Cancer stem cells (CSCs), with their self-renewal ability and multilineage differentiation potential, are a critical subpopulation of tumor cells that can drive tumor initiation, growth, and resistance to therapy. Like embryonic and adult stem cells, CSCs express markers that are not expressed in normal somatic cells and are thus thought to contribute towards a 'stemness' phenotype. This review summarizes the current knowledge of stemness-related markers in human cancers, with a particular focus on important transcription factors, protein surface markers and signaling pathways.

Identifiers

PMID29276782
PMCPMC5737740
OpenAlexW2624576378

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.