Evidence map›Paper›PMID 29276665›Full record

ArticleCurrent sleep medicine reports2017

Insights since FDA Approval of Hypoglossal Nerve Stimulation for the Treatment of Obstructive Sleep Apnea.

Madeleine M Strohl, Motoo Yamauchi, Zhe Peng, Kingman P Strohl

Abstract read
In one paragraph

Article in Current sleep medicine reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Redefining Obstructive Sleep Apnea: Treatment in the Modern Era.Pathophysiology : the official journal of the International Society for Pathophysiology · 2026
    Review
  4. Article
  5. Article
  6. Article
  7. Review
  8. Review
  9. Review
  10. Review
  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Madeleine M StrohlDepartment of Otolaryngology, University of California, San Francisco, San Francisco CA.
Motoo YamauchiDepartment of Respiratory Medicine, Nara Medical University, Nara, Japan.
Zhe PengDepartment of Surgery, People's Hospital, Peking University, Beijing, China.
Kingman P StrohlDepartment of Medicine, Division of Pulmonary, Critical Care and Sleep Medicine, Case School of Medicine, Cleveland OH.

Funding

Data Supplement Request for U18 EB021792 "A Tool for Neurotherapeutic Therapy"U18EB021792 · NIBIB · CASE WESTERN RESERVE UNIVERSITY · PI STROHL, KINGMAN PERKINS · 2015 to 2017
$1.0M
A Pre-Clinical Model for the Rehabilitation of CPAP-Intolerant Obstructive Sleep ApneaI21RX002041 · VA · LOUIS STOKES CLEVELAND VA MEDICAL CENTER · PI STROHL, KINGMAN PERKINS · 2016 to 2018
–
NIBIB NIH HHS U18 EB021792RRD VA I21 RX002041
6 · The paper itself

Abstract

purposeThe literature on hypoglossal nerve stimulation (HNS) for the treatment of moderate-to-severe obstructive sleep apnea (OSA) was reviewed from 2014, the time of FDA approval for the Inspire Systems device, to 2017 for themes that might be useful conceptually and practically in the consideration of this new non-anatomic surgical therapy. RECENT

findingsthere are now further follow-up articles since the 12-month results for Apnea Reduction (STAR) trial of the Inspire device, and post-approval publications which report similar and/0r improved AHI outcomes. Other emerging themes include drug-induced sedation endoscopy (DISE) as a tool in assessment of eligibility and a more detailed understanding of mechanisms for an HNS effects. SUMMARY: The post-STAR literature provides guidelines for an integrated coordination of medicine and surgery to appropriately screen and manage patients.

Indexed as

Clinical management OSAHypoglossal nerve stimulationNeurotheraputicsObstructive sleep apnea

Identifiers

PMID29276665
PMCPMC5739331

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.