Evidence map›Paper›PMID 29276656›Full record

ArticleCurrent genetic medicine reports2017

Primary Open-Angle Glaucoma Genetics in African Americans.

Nicole A Restrepo, Jessica N Cooke Bailey

Open access · greenAbstract read
In one paragraph

Article in Current genetic medicine reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 3 pooled it
0.2field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 3 syntheses or guidelines pooled it, 25 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Review
  5. Evaluating a virtual reality visual fields analyzer in an urban, underserved glaucoma & glaucoma suspect patient populations to identify disparities.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2025
    Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Review
  11. Article
  12. Myocilin misfolding and glaucoma: A 20-year update.Progress in retinal and eye research · 2023
    Review
  13. Glaucoma and Systemic Disease.Life (Basel, Switzerland) · 2023
    Review
  14. Article
  15. Review
  16. Article
  17. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Nicole A RestrepoDepartment of Population and Quantitative Health Sciences, Case Western Reserve University, Cleveland, OH.
Jessica N Cooke BaileyDepartment of Population and Quantitative Health Sciences, Case Western Reserve University, Cleveland, OH.
Case Western Reserve University · USCornell University · US

Funding

Clinical and Translational Science Collaborative of ClevelandKL2TR000440 · NCATS · CASE WESTERN RESERVE UNIVERSITY · PI KONSTAN, MICHAEL W. · 2012 to 2016
$11.1M
TRAINING IN COMPUTATIONAL GENOMIC EPIDEMIOLOGY OF CANCERR25CA094186 · NCI · CASE WESTERN RESERVE UNIVERSITY · PI LI, LI · 2002 to 2016
$6.8M
Computational Genomic Epidemiology of Cancer (CoGEC) Training ProgramT32CA094186 · NCI · CASE WESTERN RESERVE UNIVERSITY · PI Thomas Louis LaFramboise, Rong Xu · 2017 to 2026
$2.6M
NCATS NIH HHS KL2 TR000440NCI NIH HHS R25 CA094186NCI NIH HHS T32 CA094186
6 · The paper itself

Abstract

purpose of reviewIndividuals of African descent are at highest risk for developing primary open-angle glaucoma (POAG), a devastating disease and major contributor of blindness worldwide. Currently, there is a large dearth of knowledge in this area despite a critical need for better understanding the underlying genetic and environmental factors afflicting this population. Here we highlight the current literature exploring the genetics of POAG in African Americans. RECENT

findingsCurrent studies have yet to replicate European POAG index variants (i.e. SUMMARY: In summary, little headway has been made in elucidating the genetics of primary open-angle glaucoma in African Americans and other individuals of African descent.

Indexed as

African American primary open angle glaucomaglaucoma genetics

Identifiers

PMID29276656
PMCPMC5739069
OpenAlexW2762856878

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.