ArticleJournal of chiropractic medicine2017
Dietary Fiber Is Beneficial for the Prevention of Cardiovascular Disease: An Umbrella Review of Meta-analyses.
Article in Journal of chiropractic medicine, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 79 papers, 5 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
79 citing papers in PubMed, 5 syntheses or guidelines pooled it.
- National Heart Center/Saudi Heart Association 2025 Guidelines for Cardiovascular Diseases Prevention and Risk Assessment.Saudi medical journal · 2026Guideline
- The Role of Diet in the Prevention of Hypertension and Management of Blood Pressure: An Umbrella Review of Meta-Analyses of Interventional and Observational Studies.Advances in nutrition (Bethesda, Md.) · 2024Pooled it
- Evaluation of the Quality of Evidence of the Association of Foods and Nutrients With Cardiovascular Disease and Diabetes: A Systematic Review.JAMA network open · 2022Pooled it
- Mental health outcomes of quarantine and isolation for infection prevention: a systematic umbrella review of the global evidence.Epidemiology and health · 2020Pooled it
- Dietary Fiber Intake (Supplemental or Dietary Pattern Rich in Fiber) and Diabetic Kidney Disease: A Systematic Review of Clinical Trials.Nutrients · 2019Pooled it
- Short-chain oat fiber improves gastrointestinal tolerance and regulates glucose metabolism: a two-week open-label study in healthy adults.Frontiers in nutrition · 2026Trial
- A low-dose prebiotic fiber supplement reduces lipopolysaccharide-binding protein concentrations in a subgroup of young, healthy adults consuming low-fiber diets.Nutrition research (New York, N.Y.) · 2025Trial
- Trial
- Reduction of small dense LDL and Il-6 after intervention with Plantago psyllium in adolescents with obesity: a parallel, double blind, randomized clinical trial.European journal of pediatrics · 2021Trial
- Association of diet quality and fiber intake with carotid intima-media thickness in a young adult population of the Tehran lipid and Glucose study.Nutrition & metabolism · 2026Article
- Adipocyte-specific FFA2 deletion leads to increased adipose inflammation and is associated with altered intestinal lipid handling in mice.Physiological reports · 2026Article
- Effect of Bean-Derived Soluble Dietary Fibers on Macrophage Function In Vitro.Foods (Basel, Switzerland) · 2026Article
- Sex-specific effects of cereal-based diets on longevity and healthspan in Drosophila melanogaster.Biogerontology · 2026Article
- Protective effects of fermentable dietary fiber and propionate in Dahl salt-sensitive hypertension and renal damage.American journal of physiology. Renal physiology · 2026Article
- Global diet quality score and risk of hypertension in Iranian adults: Tehran lipid and glucose study.Public health nutrition · 2025Article
- Gender-specific protective effects of dietary index for gut microbiota on cardiovascular disease: insights from NHANES 2007-2020.BMC cardiovascular disorders · 2025Article
- Red Meat Consumption, Iron Status, and Cardiometabolic Risk in Qatari Adults: A Cross-Sectional Gender-Stratified Analysis from the QPHI-QBB Data in Qatar.Foods (Basel, Switzerland) · 2025Article
- Association of dietary preferences with cardiovascular disease: a Mendelian randomization study.Atherosclerosis plus · 2025Article
- Dietary Fibres in Processed Meat: A Review on Nutritional Enhancement, Technological Effects, Sensory Implications and Consumer Perception.Foods (Basel, Switzerland) · 2025Review
- Carbohydrate Quality Is Independently Associated with Cardiometabolic Risk in Chinese Individuals with Impaired Glucose Tolerance.Nutrients · 2025Article
19 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveThe purpose of this study was to review previously published meta-analyses on the effectiveness of dietary fiber on cardiovascular disease.
methodsAn umbrella review of all published meta-analyses was performed. A PubMed search from January 1, 1980, to January 31, 2017, was conducted using the following search strategy: (fiber OR glucan OR psyllium OR fructans) AND (meta-analysis OR systematic review). Only English-language publications that provided quantitative statistical analysis on cardiovascular disease, lipid concentrations, or blood pressure were retrieved.
resultsThirty-one meta-analyses were retrieved for inclusion in this umbrella review, and all meta-analyses comparing highest versus lowest dietary fiber intake reported statistically significant reductions in the relative risk (RR) of cardiovascular disease mortality (RR = 0.77-0.83), as well as the incidences of cardiovascular disease (RR = 0.72-0.91), coronary heart disease (RR = 0.76-0.93), and stroke (RR = 0.83-0.93). Meta-analyses on supplementation studies using β-glucan or psyllium fibers also reported statistically significant reductions in both total serum and low-density lipoprotein cholesterol concentrations.
conclusionThis review suggests that individuals consuming the highest amounts of dietary fiber intake can significantly reduce their incidence and mortality from cardiovascular disease. Mechanistically, these beneficial effects may be due to dietary fibers' actions on reducing total serum and low-density lipoprotein cholesterol concentrations between 9.3 to 14.7 mg/dL and 10.8 to 13.5 mg/dL, respectively.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.