Evidence map›Paper›PMID 29276389›Full record

ArticleTherapeutics and clinical risk management2017

Predictors of acute pancreatitis with low elevation of serum amylase.

Wandong Hong, Wujun Geng, Bicheng Chen, Zarrin Basharat, Qingsong Wu, Vincent Zimmer, Mengtao Zhou

Abstract read
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Article in Therapeutics and clinical risk management, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
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10citing papers in PubMed, 1 pooled it
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1 · What the graph read from it

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3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it.

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  8. Sex differences in the relationship among alcohol, smoking, andThe Journal of international medical research · 2020
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4 · The record

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5 · Who and what money

Authors and funding

7 authors.

Wandong Hong *Department of Gastroenterology and Hepatology.
Wujun Geng *Department of Anesthesiology.
Bicheng Chen *Department of Surgery, Zhejiang Provincial Top Key Discipline in Surgery, Wenzhou Key Laboratory of Surgery.
Zarrin Basharat *Microbiology & Biotechnology Research Lab, Department of Environmental Sciences, Fatima Jinnah Women University, Rawalpindi, Pakistan.
Qingsong WuDepartment of Medical Records, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, People's Republic of China.
Vincent ZimmerDepartment of Medicine II, Saarland University Medical Center, Saarland University, Homburg.
Mengtao ZhouDepartment of Surgery, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, People's Republic of China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND AND

aimsSerum amylase is a traditional measure used to establish the diagnosis of acute pancreatitis (AP). The current study aimed to assess the predictors and clinical outcome of AP with low serum amylase.

methodsAll patients were divided into two groups, based on their serum amylase level within the first 2 days after hospital admission: group 1 (amylase ≥300 U/L) and group 2 (amylase <300 U/L). Clinical outcomes were compared between the two groups before and after 1:1 propensity score matching. Clinical and biochemical parameters were collected and evaluated as potential predictors of AP with low serum amylase.

resultsA total of 464 patients were enrolled. After propensity score matching according to age, gender, time interval before admission, hematocrit, blood urea nitrogen and creatinine, 108 matched pairs of patients were selected. There was no significant statistical difference between group 2 and group 1 with respect to severity of AP, median days of stay in hospital and death. Multivariate analysis indicated that biliary etiology (odds ratio [OR]: 0.499; 95% confidence interval [CI]: 0.265-0.942;

conclusionSerum amylase level was not related to the severity of AP, median hospital stay (days) and death. Biliary etiology, LDL-C and triglyceride levels were independently associated with the development of AP with lower elevation of serum amylase.

Indexed as

acute pancreatitisetiologylipidspredictionrisk factorseverity

Identifiers

PMID29276389
PMCPMC5734230

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