Evidence map›Paper›PMID 29275812›Full record

ArticleSeminars in pediatric surgery2018

Development of the necrotizing enterocolitis society registry and biorepository.

Matthew W Ralls, Samir K Gadepalli, Karl G Sylvester, Misty Good

Abstract read
In one paragraph

Article in Seminars in pediatric surgery, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Article
  2. Observational
  3. Prevention Strategies and Management of Necrotizing Enterocolitis.Current treatment options in pediatrics · 2024
    Article
  4. Review
  5. Article
  6. Review
  7. Review
  8. Review
  9. Review
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Matthew W RallsSection of Pediatric Surgery, Department of Surgery, University of Michigan Health System, Ann Arbor, Michigan.
Samir K GadepalliSection of Pediatric Surgery, Department of Surgery, University of Michigan Health System, Ann Arbor, Michigan.
Karl G SylvesterDepartment of Surgery, Stanford University School of Medicine, Stanford, California; Fetal and Maternal Health Program, Lucile Packard Children's Hospital Stanford, Stanford, California.
Misty GoodDivision of Newborn Medicine, Department of Pediatrics, Washington University School of Medicine, St. Louis Children's Hospital, 660 S. Euclid Ave, Campus Box 8208, St. Louis, Missouri 63110. Electronic address: mistygood@wustl.edu.

Funding

Spectrum Stanford Center for clinical and Translational Research and EducationUL1TR001085 · NCATS · STANFORD UNIVERSITY · PI CULLEN, MARK RICHARD, GREENBERG, HARRY BERNARD · 2013 to 2017
$37.1M
Novel Anti-Inflammatory Properties of Breast Milk in Necrotizing EnterocolitisK08DK101608 · NIDDK · WASHINGTON UNIVERSITY · PI GOOD, MISTY L · 2014 to 2017
$584k
Aryl hydrocarbon receptor signaling in the pathogenesis of necrotizing enterocolitisR03DK111473 · NIDDK · WASHINGTON UNIVERSITY · PI GOOD, MISTY L · 2017 to 2018
$153k
NCATS NIH HHS UL1 TR001085NIDDK NIH HHS K08 DK101608NIDDK NIH HHS R03 DK111473
6 · The paper itself

Abstract

Necrotizing enterocolitis (NEC) is a devastating disease affecting premature infants. New advances in diagnostic and treatment options are desperately needed. Accordingly, the NEC Society initiated a research collaborative with a group of investigators dedicated to advancing the state of NEC-associated knowledge. Recent advances in high-content molecular interrogation and bio-computation (e.g., genomics, transcriptomics, proteomics, and metabolomics) can provide new insights from afflicted infants with NEC, however, individual centers do not have sufficient cases to conduct these studies independently. The development of a NEC Society Biorepository (NSB) has emerged to advance collaboration among institutions through the shared use of biologic samples in the dedicated pursuit of molecular indicators of disease and to gain greater pathophysiologic insights through research. The NSB will provide key infrastructure across several centers to harness the potential for new discoveries, while ensuring specimens are processed consistently, appropriate clinical data is collected, and privacy is maintained. The NSB will provide a comprehensive framework for sharing biological samples and clinical data through a robust and secure system that supports the investigation of research studies on NEC.

Indexed as

Enterocolitis, NecrotizingInfant, Premature, DiseasesRegistriesHumansInfant, NewbornInfant, PrematureBiorepositoryIntestineNecrotizing enterocolitisRegistrySpecimen

Identifiers

PMID29275812
PMCPMC5744883

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.