Evidence map›Paper›PMID 29275455›Full record

ArticleSkeletal radiology2018

Early detection of metastases using whole-body MRI for initial staging and routine follow-up of myxoid liposarcoma.

Natalia Gorelik, Santhosh Mauvva Venkatesh Reddy, Robert E Turcotte, Krista Goulding, Sungmi Jung, Thierry Alcindor, Thomas I Powell

Abstract read
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In one paragraph

Article in Skeletal radiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 3 pooled it
3.1field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 3 syntheses or guidelines pooled it, 51 citations in OpenAlex.

  1. Pooled it
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  5. Review
  6. Review
  7. Article
  8. Article
  9. Features of MR Imaging that Differentiate between Immunohistochemically Diagnosed Dedifferentiated Liposarcoma and Myxoid Liposarcoma.Magnetic resonance in medical sciences : MRMS : an official journal of Japan Society of Magnetic Resonance in Medicine · 2025
    Article
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  11. Article
  12. Article
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  14. Myxoid Liposarcoma: How to Stage and Follow.Current treatment options in oncology · 2023
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  16. Article
  17. Review
  18. Review
  19. Impact of Sanctions on Cancer Care in Iran.The archives of bone and joint surgery · 2018
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Natalia GorelikDepartment of Diagnostic Radiology, McGill University Health Center, Montreal, Quebec, Canada. natalia.gorelik@mail.mcgill.ca.
Santhosh Mauvva Venkatesh ReddyDepartment of Diagnostic Radiology, McGill University Health Center, Montreal, Quebec, Canada.
Robert E TurcotteDivision of Orthopaedic Surgery, McGill University Health Center, Montreal, Quebec, Canada.
Krista GouldingDivision of Orthopaedic Surgery, McGill University Health Center, Montreal, Quebec, Canada.
Sungmi JungDepartment of Pathology, McGill University Health Center, Montreal, Quebec, Canada.
Thierry AlcindorGerald Bronfman Department of Oncology, Division of Medical Oncology, McGill University Health Center, Montreal, Quebec, Canada.
Thomas I PowellDepartment of Diagnostic Radiology, McGill University Health Center, Montreal, Quebec, Canada.
McGill University Health Centre · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo define the role of whole-body MRI (WBMRI) for initial staging and routine follow-up of myxoid liposarcoma (MLS). MATERIALS AND

methodsA retrospective review of all the patients with MLS who underwent WBMRI for initial staging and routine follow-up at our institution between October 1, 2006, and September 30, 2016 was performed. Patient demographics, clinical presentation, imaging findings, tumor histology, and occurrence and location of metastatic disease were recorded. Thirty-three patients who underwent a total of 150 WBMRI examinations were included in the study.

resultsNine patients (27%) were diagnosed with metastases between 0 and 60 months (median 10; interquartile range, 7-13) from the diagnosis of the primary tumor. The initial site of metastatic disease was extrapulmonary in all patients. Only two patients developed pulmonary metastases, which were diagnosed by CT chest 9 and 29 months after the diagnosis of extrapulmonary metastases. The first metastasis was diagnosed by WBMRI in seven patients (78%), by thoracic CT in one patient, and by abdominal CT in one patient. Eight of nine patients (89%) were asymptomatic at the time of diagnosis of the metastases. In seven patients (78%), WBMRI demonstrated metastases included within the field of view of, but occult on a contemporaneous CT scan.

conclusionOur 10-year institutional experience demonstrates that WBMRI facilitates early detection of extrapulmonary MLS metastases before the onset of clinical symptoms and pulmonary metastases. WBMRI also depicts extrapulmonary metastases that are occult on CT scans. The current surveillance strategies are insufficient for screening for extrapulmonary MLS metastases.

Indexed as

AdultAgedEarly Detection of CancerFemaleHumansLiposarcoma, MyxoidMagnetic Resonance ImagingMaleMiddle AgedNeoplasm MetastasisNeoplasm StagingRetrospective StudiesWhole Body ImagingFollow-upMetastasesMyxoid liposarcomaStagingWhole-body magnetic resonance imaging

Identifiers

PMID29275455
OpenAlexW2776927360

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.