Evidence map›Paper›PMID 29275361›Full record

ReviewCancer genomics & proteomics

Applications of Support Vector Machine (SVM) Learning in Cancer Genomics.

Shujun Huang, Nianguang Cai, Pedro Penzuti Pacheco, Shavira Narrandes, Yang Wang, Wayne Xu

Abstract readReview
In one paragraph

Review in Cancer genomics & proteomics. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 669 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
669citing papers in PubMed, 4 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

669 citing papers in PubMed, 4 syntheses or guidelines pooled it.

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609 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Shujun HuangCollege of Pharmacy, Rady Faculty of Health Sciences, University of Manitoba, Winnipeg, Canada.
Nianguang CaiResearch Institute of Oncology and Hematology, CancerCare Manitoba, Winnipeg, Canada.
Pedro Penzuti PachecoResearch Institute of Oncology and Hematology, CancerCare Manitoba, Winnipeg, Canada.
Shavira NarrandesResearch Institute of Oncology and Hematology, CancerCare Manitoba, Winnipeg, Canada.
Yang WangDepartment of Computer Science, Faculty of Sciences, University of Manitoba, Winnipeg, Canada.
Wayne XuResearch Institute of Oncology and Hematology, CancerCare Manitoba, Winnipeg, Canada.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Machine learning with maximization (support) of separating margin (vector), called support vector machine (SVM) learning, is a powerful classification tool that has been used for cancer genomic classification or subtyping. Today, as advancements in high-throughput technologies lead to production of large amounts of genomic and epigenomic data, the classification feature of SVMs is expanding its use in cancer genomics, leading to the discovery of new biomarkers, new drug targets, and a better understanding of cancer driver genes. Herein we reviewed the recent progress of SVMs in cancer genomic studies. We intend to comprehend the strength of the SVM learning and its future perspective in cancer genomic applications.

Indexed as

GenomicsSupport Vector MachineBiomarkers, TumorDrug DiscoveryGenes, NeoplasmHumansNeoplasmsProtein Interaction MappingBiomarkers, Tumorbiomarker discoverycancer classificationclassifierdriver genedrug discoverygene expressiongene-gene interactiongene selectiongenomicskernel functionMachine learning (ML)reviewsupport vector machine (SVM)

Identifiers

PMID29275361
PMCPMC5822181

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.