Evidence map›Paper›PMID 29275000›Full record

ReviewFrontiers in neuroendocrinology2018

The metamorphosis of adolescent hormonal stress reactivity: A focus on animal models.

Russell D Romeo

Abstract readReview
In one paragraph

Review in Frontiers in neuroendocrinology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Russell D RomeoDepartment of Psychology and Neuroscience and Behavior Program, Barnard College of Columbia University, New York, NY 10027, United States. Electronic address: rromeo@barnard.edu.

Funding

Neural Basis of Pubertal Shifts in Stress ReactivityR03MH090224 · NIMH · BARNARD COLLEGE · PI ROMEO, RUSSELL D. · 2011 to 2012
$135k
NIMH NIH HHS R03 MH090224
6 · The paper itself

Abstract

As adolescents transition from childhood to adulthood, many physiological and neurobehavioral changes occur. Shifts in neuroendocrine function are one such change, including the hormonal systems that respond to stressors. This review will focus on these hormonal changes, with a particular emphasis on the pubertal and adolescent maturation of the hypothalamic-pituitary-adrenal (HPA) axis. Furthermore, this review will concentrate on studies using animal models, as these model systems have contributed a great deal to our mechanistic understanding of how factors such as sex and experience with stressors shape hormonal reactivity during development. Continued study of the maturation of stress reactivity will undoubtedly shed much needed light on the stress-related vulnerabilities often associated with adolescence as well as providing us with possible strategies to mitigate these vulnerabilities. This area of research may lead to discoveries that enhance the well-being of adolescents, ultimately providing them with greater opportunities to mature into healthy adults.

Indexed as

Disease Models, AnimalAnimalsHumansHypothalamo-Hypophyseal SystemPituitary-Adrenal SystemSexual MaturationStress, PsychologicalAdolescenceDevelopmentalHPA axisMaturationPuberty

Identifiers

PMID29275000
PMCPMC5963973

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.