ArticleArchives of physical medicine and rehabilitation2018
Dynamic Balance Is Related to Physiological Impairments in Persons With Multiple Sclerosis.
Article in Archives of physical medicine and rehabilitation, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05937971 (Examination of the Implications of Plantar Sensitivity Training and Aerobic Exercise Training on Balance, Functional Capacity, Gait and Proprioception in Patients With Multiple Sclerosis), which is not on this map. Cited by 13 papers.
What it found
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Examination of the Implications of Plantar Sensitivity Training and Aerobic Exercise Training on Balance, Functional Capacity, Gait and Proprioception in Patients With Multiple Sclerosis
Who cites it
13 citing papers in PubMed.
- Distinct correlations between clinical and laboratory-based instrumented balance measures in individuals with multiple sclerosis: a cross-sectional study.Scientific reports · 2026Article
- Assessment of Dog-Leash Pulling Force and the Impact of Dog-Walking on Gait Kinematics.Annals of biomedical engineering · 2026Article
- Fall history moderates the relationship between concern about falling and reactive stepping performance in people with multiple sclerosis.Neuroscience · 2025Article
- Multiple Sclerosis Classification Using the Local Divergence Exponent: Parameters Selection for State-Space Reconstruction.Sensors (Basel, Switzerland) · 2025Article
- Testing Dynamic Balance in People with Multiple Sclerosis: A Correlational Study between Standard Posturography and Robotic-Assistive Device.Sensors (Basel, Switzerland) · 2024Article
- Using the Instrumented Sway System (ISway) to Identify and Compare Balance Domain Deficits in People With Multiple Sclerosis.Archives of physical medicine and rehabilitation · 2023Article
- Humans prioritize walking efficiency or walking stability based on environmental risk.PloS one · 2023Article
- Examining the Relationship Between Reactive Stepping Outcomes and Falls in People With Multiple Sclerosis.Physical therapy · 2022Article
- Measuring Gait Stability in People with Multiple Sclerosis Using Different Sensor Locations and Time Scales.Sensors (Basel, Switzerland) · 2021Article
- Trunk and foot acceleration variability during walking relates to fall history and clinical disability in persons with multiple sclerosis.Clinical biomechanics (Bristol, Avon) · 2020Article
- Correlation between spinal cord diffusion tensor imaging and postural response latencies in persons with multiple sclerosis: A pilot study.Magnetic resonance imaging · 2020Article
- Non-linear measures of movement variability in multiple sclerosis: a clinical narrative review of Lyapunov exponent and entropy applications in balance and gait.Frontiers in neurologyReview
- Increased ankle muscle coactivation in the early stages of multiple sclerosis.Multiple sclerosis journal - experimental, translational and clinicalArticle
Corrections and comments
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Authors and funding
4 authors.
Funding
Abstract
objectivesTo compare physiological impairments between persons with multiple sclerosis (MS) with a history of falls and persons with MS without a history of falls, and to investigate the association between physiological impairments and dynamic balance.
designCross-sectional study.
settingUniversity motion analysis laboratory.
participantsPersons with MS (N=55; 27 recurrent fallers and 28 nonfallers). Participants were classified as fallers if they self-reported ≥2 falls in the previous 6 months.
interventionsNone.
main outcome measuresPhysiological impairment was assessed with sensorimotor delays, spasticity, plantar cutaneous sensation, and the sensory, cerebellar, and pyramidal subscales of the Expanded Disability Status Scale (EDSS). Dynamic balance was assessed using the average and variability of margin of stability and variability of trunk accelerations.
resultsCompared with nonfallers, fallers had lower plantar sensation, longer sensorimotor delays, more spasticity, and more impairment in the pyramidal and cerebellar subscales of the EDSS. Additionally, these impairments were all moderately to strongly correlated with worse dynamic balance.
conclusionsThis study highlights the multifactorial nature of instability in persons with MS. A better understanding of the physiological mechanisms of dynamic instability in persons with MS can be used to improve methods of monitoring disease progression, identifying which impairments to target through interventions, and appropriately evaluating intervention efficacy.
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Registered trials
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