SynthesisJournal of the American Geriatrics Society2018
Temporal Trends in Analgesic Use in Long-Term Care Facilities: A Systematic Review of International Prescribing.
Synthesis in Journal of the American Geriatrics Society, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- A systematic review of opioid prevalence in Australian residential aged care facilities.Australasian journal on ageing · 2022Pooled it
- Algorithm-based pain management for people with dementia in nursing homes.The Cochrane database of systematic reviews · 2022Pooled it
- Mechanisms and Characteristics of Chronic Pain in Alzheimer's Disease: A Narrative Review.Current medicinal chemistry · 2026Review
- Comparison of opioid use among long-term care residents in Ontario and Alberta, Canada: A multi-jurisdictional, repeated cross-sectional study.Canadian journal of pain = Revue canadienne de la douleur · 2025Article
- A mixed-methods study on the pharmacological management of pain in Australian and Japanese nursing homes.Age and ageing · 2024Article
- Identifying Residents Who May Benefit from an Analgesic Review: Applying Analgesic Indicators in Residential Aged Care Services.Drugs & aging · 2023Review
- Demographic and clinical profiles of residents in long-term care facilities in South Africa: A cross-sectional survey.African journal of primary health care & family medicine · 2022Article
- Interventions to optimize medication use in nursing homes: a narrative review.European geriatric medicine · 2021Review
- Article
- [Pain in dementia].Schmerz (Berlin, Germany) · 2021Review
- Regional Differences in Prescribing Patterns of Metamizole in Germany Based on Data from 70 Million Persons.International journal of environmental research and public health · 2020Article
- The Use of Opioids and Antipsychotics in Elderly with Dementia - Have Opioids Replaced Antipsychotics in Treating Behavioral Symptoms in Dementia?Journal of Alzheimer's disease : JAD · 2020Article
- Pain Assessment, Management, and Impact Among Older Adults in Assisted Living.Pain management nursing : official journal of the American Society of Pain Management Nurses · 2019Review
- Analgesic prescribing trends in a national sample of older veterans with osteoarthritis: 2012-2017.Pain · 2019Article
- The knowledge and attitudes of general practitioners to the assessment and management of pain in people with dementia.BMC family practice · 2018Article
- Commonly Initiated Opioids and Risk of Fracture Hospitalizations in United States Nursing Homes.Drugs & aging · 2018Article
- Pain in dementia.Pain reportsArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
Abstract
objectivesTo explore global changes in the prescription of analgesic drugs over time in the international long-term care (LTC) population.
designSystematic review.
settingWe included original research articles in English, published and unpublished, that included number of participants, country and year(s) of data collection, and prescription of analgesics (analgesics not otherwise specified, opioids, acetaminophen; scheduled only, or scheduled plus as needed (PRN)).
participantsLTC residents. MEASUREMENTS: We searched PubMed, EMBASE, CINAHL, International Pharmaceutical Abstracts, PsycINFO, Cochrane, Web of Science, Google Scholar, using keywords for LTC facilities and analgesic medication; hand-searched references of eligible papers; correspondence. Studies were quality rated using an adapted Newcastle-Ottawa scale. Pearson correlation coefficients were generated between percentage of residents prescribed an analgesic and year of data collection. If available, we investigated changes in acetaminophen and opioid prescriptions.
resultsForty studies met inclusion criteria. A moderate correlation (0.59) suggested that scheduled prescription rates for analgesics have increased over time. Similar findings were reflected in scheduled prescriptions for acetaminophen and opioids. No increase was seen when analyzing scheduled plus PRN analgesics. Use of opioids (scheduled plus PRN) appears to have increased over time.
conclusionWorldwide, use of opioids and acetaminophen has increased in LTC residents. Research is needed to explore whether this reflects appropriate pain management for LTC residents and if PRN medication is used effectively.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.