ArticleClinical transplantation2018
The sarcopenia index: A novel measure of muscle mass in lung transplant candidates.
Article in Clinical transplantation, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers, 1 of them a synthesis that pooled it.
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Who cites it
39 citing papers in PubMed, 1 synthesis or guideline pooled it, 92 citations in OpenAlex.
- Serum creatinine/cystatin C ratio as a muscle mass evaluating tool and prognostic indicator for hospitalized patients: A meta-analysis.Frontiers in medicine · 2022Pooled it
- Role of Renal Biomarkers in Sarcopenia or Frailty in Patients With Liver Cirrhosis.Journal of Korean medical science · 2026Article
- Prevalence and Clinical Correlates of Sarcopenia and Malnutrition in Lung Transplant Recipients Using EWGSOP2 and GLIM Criteria.Nutrients · 2026Article
- Creatinine muscle index in UK Biobank: comparison with MRI and associations with frailty and mortality.Clinical kidney journal · 2026Article
- Sarcopenia Index trajectories predict long-term mortality in super-elderly patients with sepsis: a retrospective cohort study.Frontiers in medicine · 2026Article
- Influence of divergence in residual feed intake on growth performance, carcass traits, meat quality, muscle fiber morphology, and blood chemistry in indigenous chickens.Poultry science · 2025Article
- Association between sarcopenia index and the risk of second hip fracture in older adults.The journal of nutrition, health & aging · 2025Article
- Relationships Between Nutrition Risk and Frailty in Candidates for Lung Transplant.Clinical transplantation · 2025Article
- Serum creatinine to cystatin C ratio as monitoring biomarker in Chinese adult spinal muscular atrophy: a prospective cohort study.Orphanet journal of rare diseases · 2025Observational
- Cystatin-c / total cholesterol ratio as a predictor of probable sarcopenia in geriatric population from 12 European countries.Aging clinical and experimental research · 2025Article
- Oral Frailty and Its Relationship with Physical Frailty in Older Adults: A Longitudinal Study Using the Oral Frailty Five-Item Checklist.Nutrients · 2024Article
- Lower serum creatinine to cystatin C ratio associated with increased incidence of frailty in community-dwelling elderly men but not in elderly women.Aging clinical and experimental research · 2024Article
- Diabetes Mellitus Should Be Considered While Analysing Sarcopenia-Related Biomarkers.Journal of clinical medicine · 2024Review
- Current approach to the diagnosis of sarcopenia in cardiovascular diseases.Frontiers in nutrition · 2024Review
- Article
- The Association between Serum Creatinine/Cystatin C Ratio and Cardiovascular Morbidity and Mortality: Insights from NHANES.Reviews in cardiovascular medicine · 2023Article
- Diagnostic Value of Serum Creatinine and Cystatin-C-Based Indices and Ishii Score in Cancer-Related Sarcopenia.Diagnostics (Basel, Switzerland) · 2023Article
- Clinical significance of serum cystatin C-to-creatinine ratio as a surrogate marker for incident osteoporotic fracture predictions.Journal of general and family medicine · 2023Article
- Article
- Serum creatinine/cystatin C ratio is a predictor of all-cause mortality for older adults over 80 years.Heliyon · 2023Article
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
Abstract
backgroundFrailty, including low muscle mass, is an emerging risk factor for poor outcomes after lung transplant. The sarcopenia index (SI)-(serum creatinine value/cystatin C value) × 100-is a novel blood test to approximate muscle mass. We sought to validate SI among lung transplant patients.
methodsWe retrospectively identified adult lung transplant recipients from 2000 through 2012 at our institution who underwent computed tomography within 1 year before transplant and had preserved blood samples. Creatinine and cystatin C values were measured using the samples and used to calculate SI. Muscle mass was estimated by computed tomographic measurement of skeletal muscle cross-sectional surface area (SA) at the L1 to L3 vertebral levels. Correlation between SI and SA was evaluated.
resultsOf 28 patients meeting eligibility criteria, most were white (96%) and men (54%). Median (interquartile range) body mass index, SI, and SA were 25.9 (22-30) kg/m
conclusionSarcopenia index is a potentially objective measure for estimating muscle mass that is noninvasive and less expensive. Sarcopenia index could be considered in lung transplant candidate selection following prospective validation in larger cohorts.
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Registered trials
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