ArticleeLife2017
Cortical response states for enhanced sensory discrimination.
Article in eLife, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
16 citing papers in PubMed, 26 citations in OpenAlex.
- Unsupervised learning of temporal regularities in visual cortical populations.Nature communications · 2025Article
- Network mechanisms of ongoing brain activity's influence on conscious visual perception.Nature communications · 2024Article
- Endogenous fluctuations in cortical state selectively enhance different modes of sensory processing in human temporal lobe.Nature communications · 2023Article
- Distractibility and impulsivity neural states are distinct from selective attention and modulate the implementation of spatial attention.Nature communications · 2022Article
- Enhanced brainstem phase-locking in low-level noise reveals stochastic resonance in the frequency-following response (FFR).Brain research · 2021Review
- Unsupervised Learning and Clustered Connectivity Enhance Reinforcement Learning in Spiking Neural Networks.Frontiers in computational neuroscience · 2021Article
- Revisiting Persistent Neuronal Activity During Covert Spatial Attention.Frontiers in neural circuits · 2021Review
- Slow Drift of Neural Activity as a Signature of Impulsivity in Macaque Visual and Prefrontal Cortex.Neuron · 2020Article
- The Effects of Population Tuning and Trial-by-Trial Variability on Information Encoding and Behavior.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2020Article
- Task-Demand-Dependent Neural Representation of Odor Information in the Olfactory Bulb and Posterior Piriform Cortex.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2019Article
- Distinct Waking States for Strong Evoked Responses in Primary Visual Cortex and Optimal Visual Detection Performance.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2019Article
- Functional flexibility in cortical circuits.Current opinion in neurobiology · 2019Review
- High-order coordination of cortical spiking activity modulates perceptual accuracy.Nature neuroscience · 2019Article
- Neuromodulation influences synchronization and intrinsic read-out.F1000Research · 2018Article
- Understanding Sensory Information Processing Through Simultaneous Multi-area Population Recordings.Frontiers in neural circuits · 2018Article
- The Interplay Between Cortical State and Perceptual Learning: A Focused Review.Frontiers in systems neuroscience · 2018Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 2 countries.
Funding
Abstract
Brain activity during wakefulness is characterized by rapid fluctuations in neuronal responses. Whether these fluctuations play any role in modulating the accuracy of behavioral responses is poorly understood. Here, we investigated whether and how trial changes in the population response impact sensory coding in monkey V1 and perceptual performance. Although the responses of individual neurons varied widely across trials, many cells tended to covary with the local population. When population activity was in a 'low' state, neurons had lower evoked responses and correlated variability, yet higher probability to predict perceptual accuracy. The impact of firing rate fluctuations on network and perceptual accuracy was strongest 200 ms before stimulus presentation, and it greatly diminished when the number of cells used to measure the state of the population was decreased. These findings indicate that enhanced perceptual discrimination occurs when population activity is in a 'silent' response mode in which neurons increase information extraction.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.