ArticleActa neurochirurgica2018
ICP curve morphology and intracranial flow-volume changes: a simultaneous ICP and cine phase contrast MRI study in humans.
Article in Acta neurochirurgica, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.
What it found
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
14 citing papers in PubMed, 1 synthesis or guideline pooled it, 37 citations in OpenAlex.
- Cerebral blood flow, autoregulation and vascular reactivity in normal pressure hydrocephalus: a systematic review.Fluids and barriers of the CNS · 2025Pooled it
- Continuous Measurement in Neurocritical Care of Cerebral Blood Flow (CBF) Calculated from ICP and Central Venous Pressure.Neurology international · 2025Article
- Continuous measurement in neurocritical care of cerebral blood flow (CBF) calculated from ICP and central venous pressure.Scientific reports · 2024Article
- Cerebrovascular Responses in a Patient with Lundberg B Waves Following Subarachnoid Haemorrhage Assessed with a Novel Non-Invasive Brain Pulse Monitor: A Case Report.Medical devices (Auckland, N.Z.) · 2024Article
- Noninvasive intracranial pressure profile in 31 patients submitted to fullendoscopic spine surgery.Acta cirurgica brasileira · 2024Article
- Article
- Stationary flow driven by non-sinusoidal time-periodic pressure gradients in wavy-walled channels.Applied mathematical modelling · 2023Article
- Cerebral arterial flow dynamics during systole and diastole phases in young and older healthy adults.Fluids and barriers of the CNS · 2023Article
- A Deep Learning-Based Automated Framework for Subpeak Designation on Intracranial Pressure Signals.Sensors (Basel, Switzerland) · 2023Article
- Human intracranial pulsatility during the cardiac cycle: a computational modelling framework.Fluids and barriers of the CNS · 2022Article
- A one-dimensional model for the pulsating flow of cerebrospinal fluid in the spinal canal.Journal of fluid mechanics · 2022Article
- A novel rat model for cerebral venous sinus thrombosis: verification of similarity to human disease via clinical analysis and experimental validation.Journal of translational medicine · 2022Article
- Validation of a mathematical model for understanding intracranial pressure curve morphology.Journal of clinical monitoring and computing · 2020Article
- The intracranial pressure curve correlates to the pulsatile component of cerebral blood flow.Journal of clinical monitoring and computing · 2019Article
Corrections and comments
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Authors and funding
3 authors at 2 institutions in 2 countries.
Funding
Abstract
backgroundThe intracranial pressure (ICP) curve with its different peaks has been extensively studied, but the exact physiological mechanisms behind its morphology are still not fully understood. Both intracranial volume change (ΔICV) and transmission of the arterial blood pressure have been proposed to shape the ICP curve. This study tested the hypothesis that the ICP curve correlates to intracranial volume changes.
methodsCine phase contrast magnetic resonance imaging (MRI) examinations were performed in neuro-intensive care patients with simultaneous ICP monitoring. The MRI was set to examine cerebral arterial inflow and venous cerebral outflow as well as flow of cerebrospinal fluid over the foramen magnum. The difference in total flow into and out from the cranial cavity (Flow
resultsExcluding the initial ICP wave, P1, the mean R
conclusionThe first part, or the P1, of the ICP curve seems to be created by the first rapid net inflow seen in Flow
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.