Evidence map›Paper›PMID 29273904›Full record

ReviewAnalytical and bioanalytical chemistry2018

Advanced LC-MS-based methods to study the co-occurrence and metabolization of multiple mycotoxins in cereals and cereal-based food.

Alexandra Malachová, Milena Stránská, Marta Václavíková, Christopher T Elliott, Connor Black, Julie Meneely, Jana Hajšlová, Chibundu N Ezekiel, Rainer Schuhmacher, Rudolf Krska

Abstract readReview
In one paragraph

Review in Analytical and bioanalytical chemistry, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 58 papers.

0numbers the graph read from it
0cells of the map it votes in
58citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

58 citing papers in PubMed.

  1. Article
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  10. Peanuts (Foods (Basel, Switzerland) · 2025
    Review
  11. Article
  12. Article
  13. Review
  14. Article
  15. Article
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  17. Analytical chemistry in front of the curtain!Analytical and bioanalytical chemistry · 2024
    Article
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Alexandra MalachováCenter for Analytical Chemistry, Department of Agrobiotechnology (IFA-Tulln), University of Natural Resources and Life Sciences, Vienna (BOKU), Konrad Lorenz Str. 20, 3430, Tulln, Austria.
Milena StránskáDepartment of Food Analysis & Nutrition, Faculty of Food & Biochemical Technology, University of Chemistry & Technology, Technická 3, 166 28, Prague 6, Czech Republic.
Marta VáclavíkováCenter for Analytical Chemistry, Department of Agrobiotechnology (IFA-Tulln), University of Natural Resources and Life Sciences, Vienna (BOKU), Konrad Lorenz Str. 20, 3430, Tulln, Austria.
Christopher T ElliottInstitute for Global Food Security, School of Biological Sciences, Queens University Belfast, 18-30 Malone Road, Belfast, BT9 5BN, UK.
Connor BlackInstitute for Global Food Security, School of Biological Sciences, Queens University Belfast, 18-30 Malone Road, Belfast, BT9 5BN, UK.
Julie MeneelyInstitute for Global Food Security, School of Biological Sciences, Queens University Belfast, 18-30 Malone Road, Belfast, BT9 5BN, UK.
Jana HajšlováDepartment of Food Analysis & Nutrition, Faculty of Food & Biochemical Technology, University of Chemistry & Technology, Technická 3, 166 28, Prague 6, Czech Republic.
Chibundu N EzekielDepartment of Microbiology, Babcock University, Ilishan Remo, Ogun State, 121103, Nigeria.
Rainer SchuhmacherCenter for Analytical Chemistry, Department of Agrobiotechnology (IFA-Tulln), University of Natural Resources and Life Sciences, Vienna (BOKU), Konrad Lorenz Str. 20, 3430, Tulln, Austria.
Rudolf KrskaCenter for Analytical Chemistry, Department of Agrobiotechnology (IFA-Tulln), University of Natural Resources and Life Sciences, Vienna (BOKU), Konrad Lorenz Str. 20, 3430, Tulln, Austria. rudolf.krska@boku.ac.at.

Funding

MultiCoop This work has received funding from the European U
6 · The paper itself

Abstract

Liquid chromatography (LC) coupled with mass spectrometry (MS) is widely used for the determination of mycotoxins in cereals and cereal-based products. In addition to the regulated mycotoxins, for which official control is required, LC-MS is often used for the screening of a large range of mycotoxins and/or for the identification and characterization of novel metabolites. This review provides insight into the LC-MS methods used for the determination of co-occurring mycotoxins with special emphasis on multiple-analyte applications. The first part of the review is focused on targeted LC-MS approaches using cleanup methods such as solid-phase extraction and immunoaffinity chromatography, as well as on methods based on minimum cleanup (quick, easy, cheap, effective, rugged, and safe; QuEChERS) and dilute and shoot. The second part of the review deals with the untargeted determination of mycotoxins by LC coupled with high-resolution MS, which includes also metabolomics techniques to study the fate of mycotoxins in plants.

Indexed as

Chromatography, AffinityChromatography, High Pressure LiquidEdible GrainFood AnalysisFungiMetabolomicsMycotoxinsSolid Phase ExtractionTandem Mass SpectrometryMycotoxinsFungal secondary metabolitesLiquid chromatography–high-resolution mass spectrometryLiquid chromatography–tandem mass spectrometryMetabolomicsValidation

Identifiers

PMID29273904
PMCPMC5775372

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.