Evidence map›Paper›PMID 29273844›Full record

ArticleJournal of neurology2018

Attitudes, perceptions, and use of marijuana in youth with multiple sclerosis.

J Nicholas Brenton, Teri Schreiner, Krystle Karoscik, Meg Richter, Samantha Ferrante, Amy Waldman, Brenda Banwell

Abstract read
PubMed Publisher
In one paragraph

Article in Journal of neurology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
0.4field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 13 citations in OpenAlex.

  1. Immunomodulatory Potential of Cannabidiol in Multiple Sclerosis: a Systematic Review.Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology · 2021
    Pooled it
  2. Article
  3. Under the Influence: Cognitive Effects of Medical Marijuana on Developing Minds.The journal of pediatric pharmacology and therapeutics : JPPT : the official journal of PPAG · 2025
    Article
  4. Article
  5. Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

J Nicholas BrentonDivision of Pediatric Neurology, Department of Neurology, University of Virginia, PO Box 800394, Charlottesville, VA, 22908, USA. jnb8h@virginia.edu.ORCID http://orcid.org/0000-0001-9432-1347
Teri SchreinerDepartment of Pediatric Neurology, University of Colorado/Children's Hospital Colorado, Aurora, CO, USA.
Krystle KaroscikDepartment of Pediatric Neurology, University of Pennsylvania/Children's Hospital of Philadelphia, Philadelphia, PA, USA.
Meg RichterDepartment of Pediatric Neurology, University of Pennsylvania/Children's Hospital of Philadelphia, Philadelphia, PA, USA.
Samantha FerranteDepartment of Pediatric Neurology, University of Pennsylvania/Children's Hospital of Philadelphia, Philadelphia, PA, USA.
Amy WaldmanDepartment of Pediatric Neurology, University of Pennsylvania/Children's Hospital of Philadelphia, Philadelphia, PA, USA.
Brenda BanwellDepartment of Pediatric Neurology, University of Pennsylvania/Children's Hospital of Philadelphia, Philadelphia, PA, USA.
Children's Hospital of Philadelphia · USChildren's Hospital Colorado · USUniversity of Virginia · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundStudies have shown a negative impact on cognition and brain volume in marijuana-using adult multiple sclerosis (MS) patients and healthy adolescents. Given that onset of MS during childhood and adolescence negatively impacts brain growth and the normal maturation of neuronal networks, the addition of marijuana exposure in these youth may be even more harmful.

objectiveDetermine attitudes toward and prevalence of recreational marijuana use in MS youth.

methodsWe surveyed 52 consecutive pediatric-onset MS patients from three pediatric MS centers in the United States. Participants answered a structured questionnaire to capture attitudes toward marijuana and personal use habits, if present.

resultsNearly half reported use of marijuana, with the majority beginning to use in mid-to-late adolescence. The most popular reasons for using marijuana were relaxation (72%), improvement of medical problems (64%), and stress reduction (52%). Over half (64%) of marijuana users perceived it to have negative effects on memory and focus. Cost and access were not barriers to use, despite all respondents being less than age 21.

conclusionYouth with MS endorse recreational marijuana as safe, and many use marijuana frequently despite appreciating a negative impact on memory. More detailed understanding of the long-term impact of marijuana use in youth with MS is needed.

Indexed as

AttitudeMultiple SclerosisAdolescentChildFemaleHabitsHumansKnowledgeMaleMarijuana AbuseMarijuana SmokingPerceptionPrevalenceSurveys and QuestionnairesYoung AdultAdolescentCannabisMarijuanaMultiple sclerosisPediatric

Identifiers

PMID29273844
OpenAlexW2776083792

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.