Evidence map›Paper›PMID 29273819›Full record

ReviewArchives of toxicology2018

Nanomaterials: certain aspects of application, risk assessment and risk communication.

Peter Laux, Jutta Tentschert, Christian Riebeling, Albert Braeuning, Otto Creutzenberg, Astrid Epp, Valérie Fessard, Karl-Heinz Haas, Andrea Haase, Kerstin Hund-Rinke and 9 more

Abstract readReview
In one paragraph

Review in Archives of toxicology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Analyzing Molecular Determinants of Nanodrugs' Cytotoxic Effects.International journal of molecular sciences · 2025
    Pooled it
  2. Review
  3. Review
  4. Review
  5. Emerging occupational risks in green jobs: a review.International journal of occupational medicine and environmental health · 2024
    Review
  6. Article
  7. Bacterial nano-factories as a tool for the biosynthesis of TiOApplied biochemistry and biotechnology · 2024
    Review
  8. Article
  9. Review
  10. Review
  11. Review
  12. Article
  13. Review
  14. Article
  15. Review
  16. Article
  17. Challenges in Nanomaterial Characterization - From Definition to Analysis.Advances in experimental medicine and biology · 2022
    Article
  18. Review
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors.

Peter LauxDepartment of Chemical and Product Safety, German Federal Institute for Risk Assessment (BfR), Max-Dohrn-Strasse 8-10, 10589, Berlin, Germany. peter.laux@bfr.bund.de.ORCID http://orcid.org/0000-0002-0351-3392
Jutta TentschertDepartment of Chemical and Product Safety, German Federal Institute for Risk Assessment (BfR), Max-Dohrn-Strasse 8-10, 10589, Berlin, Germany.
Christian RiebelingDepartment of Chemical and Product Safety, German Federal Institute for Risk Assessment (BfR), Max-Dohrn-Strasse 8-10, 10589, Berlin, Germany.
Albert BraeuningDepartment of Food Safety, German Federal Institute for Risk Assessment (BfR), Max-Dohrn-Strasse 8-10, 10589, Berlin, Germany.
Otto CreutzenbergDepartment of Inhalation Toxicology, Fraunhofer-Institute for Toxicology and Experimental Medicine (ITEM), Nikolai Fuchs Strasse 1, 30625, Hannover, Germany.
Astrid EppDepartment of Risk Communication, German Federal Institute for Risk Assessment (BfR), Max-Dohrn-Strasse 8-10, 10589, Berlin, Germany.
Valérie FessardLaboratoire de Fougères, French Agency for Food, Environmental and Occupational Health and Safety (ANSES), 10B Rue Claude Bourgelat, 35306, Fougères Cedex, France.
Karl-Heinz HaasFraunhofer Institute for Silicate Research ISC, Neunerplatz 2, 97082, Würzburg, Germany.
Andrea HaaseDepartment of Chemical and Product Safety, German Federal Institute for Risk Assessment (BfR), Max-Dohrn-Strasse 8-10, 10589, Berlin, Germany.
Kerstin Hund-RinkeFraunhofer Institute for Molecular Biology and Applied Ecology IME, Auf Dem Aberg 1, 57392, Schmallenberg, Germany.
Norbert JakubowskiDivision 1.1 Inorganic Trace Analysis, Federal Institute for Materials Research and Testing (BAM), Richard-Willstaetter-Str. 11, 12489, Berlin, Germany.
Peter KearnsOECD Environment, Health and Safety Division 2, rue Andre-Pascal, 75775, Paris Cedex 16, France.
Alfonso LampenDepartment of Food Safety, German Federal Institute for Risk Assessment (BfR), Max-Dohrn-Strasse 8-10, 10589, Berlin, Germany.
Hubert RauscherJoint Research Centre (JRC) of the European Commission, Directorate Health, Consumers and Reference Materials, Via E. Fermi, 2749, 21027, Ispra, Italy.
Reinhilde SchoonjansScientific Committee and Emerging Risks Unit, European Food Safety Authority (EFSA), Via Carlo Magno 1a, 43126, Parma, Italy.
Angela StörmerFraunhofer Institute for Process Engineering and Packaging IVV, Giggenhauser Strasse 35, 85354, Freising, Germany.
Axel ThielmannFraunhofer Institute for Systems and Innovation Research ISI, Breslauer Strasse 48, 76139, Karlsruhe, Germany.
Uwe MühleFraunhofer Institute for Ceramic Technologies and Systems IKTS, Winterbergstr. 28, 01277, Dresden, Germany.
Andreas LuchDepartment of Chemical and Product Safety, German Federal Institute for Risk Assessment (BfR), Max-Dohrn-Strasse 8-10, 10589, Berlin, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Development and market introduction of new nanomaterials trigger the need for an adequate risk assessment of such products alongside suitable risk communication measures. Current application of classical and new nanomaterials is analyzed in context of regulatory requirements and standardization for chemicals, food and consumer products. The challenges of nanomaterial characterization as the main bottleneck of risk assessment and regulation are presented. In some areas, e.g., quantification of nanomaterials within complex matrices, the establishment and adaptation of analytical techniques such as laser ablation inductively coupled plasma mass spectrometry and others are potentially suited to meet the requirements. As an example, we here provide an approach for the reliable characterization of human exposure to nanomaterials resulting from food packaging. Furthermore, results of nanomaterial toxicity and ecotoxicity testing are discussed, with concluding key criteria such as solubility and fiber rigidity as important parameters to be considered in material development and regulation. Although an analysis of the public opinion has revealed a distinguished rating depending on the particular field of application, a rather positive perception of nanotechnology could be ascertained for the German public in general. An improvement of material characterization in both toxicological testing as well as end-product control was concluded as being the main obstacle to ensure not only safe use of materials, but also wide acceptance of this and any novel technology in the general public.

Indexed as

Administration, OralAnimalsDisinfectantsEcotoxicologyEnvironmental ExposureFood PackagingGermanyHumansIndustryInhalation ExposureLegislation, FoodNanostructuresPublic OpinionRisk AssessmentDisinfectantsEcotoxicityExposureNanomaterialsStandardizationToxicity

Identifiers

PMID29273819
PMCPMC5773666

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.