Evidence map›Paper›PMID 29273733›Full record

ArticleScientific reports2017

Knockdown of long non-coding RNA H19 inhibits multiple myeloma cell growth via NF-κB pathway.

Yuanyuan Sun, Jing Pan, Ning Zhang, Wei Wei, Shanshan Yu, Limei Ai

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers.

0numbers the graph read from it
0cells of the map it votes in
41citing papers in PubMed
2.8field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

41 citing papers in PubMed, 66 citations in OpenAlex.

  1. Review
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  4. International journal of molecular sciences · 2026
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  8. bioRxiv : the preprint server for biology · 2024
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  10. Review
  11. Whole Transcriptome Analysis of Intervention Effect ofCurrent issues in molecular biology · 2023
    Article
  12. Long non‑coding RNAs in multiple myeloma (Review).International journal of oncology · 2023
    Review
  13. Classification of Parkinson's disease motor phenotype: a machine learning approach.Journal of neural transmission (Vienna, Austria : 1996) · 2022
    Article
  14. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Yuanyuan SunDepartment of Hematology, the First Affiliated Hospital of Jinzhou Medical University, Jinzhou, Liaoning, China.
Jing PanDepartment of Hematology, the First Affiliated Hospital of Jinzhou Medical University, Jinzhou, Liaoning, China.
Ning ZhangDepartment of Hematology, the First Affiliated Hospital of Jinzhou Medical University, Jinzhou, Liaoning, China.
Wei WeiDepartment of Hematology, the First Affiliated Hospital of Jinzhou Medical University, Jinzhou, Liaoning, China.
Shanshan YuDepartment of Hematology, the First Affiliated Hospital of Jinzhou Medical University, Jinzhou, Liaoning, China.
Limei AiDepartment of Hematology, the First Affiliated Hospital of Jinzhou Medical University, Jinzhou, Liaoning, China. yihaidaohang@163.com.
Jinzhou Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Long non-coding RNAs (lncRNAs) are implicated in the complex network of cancer including Multiple myeloma (MM) and play important roles in tumor development. lncH19 was significantly up-regulated in multiple cancer types, suggesting it is a potential oncogene. However, the exact functions and downstream mechanisms are largely unknown. This study aimed to investigate whether H19 participates in the cell growth of MM and elucidate the underlying mechanism. We found that H19 was abnormally overexpressed in MM cell lines and sorted CD138

Indexed as

Cell Line, TumorCell ProliferationFemaleGene Expression Regulation, NeoplasticGene Knockdown TechniquesHumansMaleMultiple MyelomaNeoplasm InvasivenessNF-kappa BRNA, Long NoncodingSignal TransductionH19 long non-coding RNANF-kappa BRNA, Long Noncoding

Identifiers

PMID29273733
PMCPMC5741752
OpenAlexW2780288499

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.