Evidence map›Paper›PMID 29273673›Full record

ArticleFASEB journal : official publication of the Federation of American Societies for Experimental Biology2018

Reduced SERCA activity underlies dysregulation of Ca

Thomas P Keeley, Richard C M Siow, Ron Jacob, Giovanni E Mann

Open access · bronzeAbstract read
In one paragraph

Article in FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
0.4field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 21 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Revisiting reactive oxygen species production in hypoxia.Pflugers Archiv : European journal of physiology · 2024
    Review
  6. Review
  7. Article
  8. Article
  9. Article
  10. Review
  11. Article
  12. Endothelial CaInternational journal of molecular sciences · 2019
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Thomas P KeeleyKing's British Heart Foundation Centre for Research Excellence, School of Cardiovascular Medicine and Sciences, Faculty of Life Sciences and Medicine, King's College London, London, United Kingdom.
Richard C M SiowKing's British Heart Foundation Centre for Research Excellence, School of Cardiovascular Medicine and Sciences, Faculty of Life Sciences and Medicine, King's College London, London, United Kingdom.
Ron JacobKing's British Heart Foundation Centre for Research Excellence, School of Cardiovascular Medicine and Sciences, Faculty of Life Sciences and Medicine, King's College London, London, United Kingdom.
Giovanni E MannKing's British Heart Foundation Centre for Research Excellence, School of Cardiovascular Medicine and Sciences, Faculty of Life Sciences and Medicine, King's College London, London, United Kingdom.
King's College London · GB

Funding

British Heart Foundation FS/13/66/30445
6 · The paper itself

Abstract

Unregulated increases in cellular Ca

Indexed as

Calcium SignalingCalciumCalcium-Binding ProteinsCell DeathHumansHuman Umbilical Vein Endothelial CellsHyperoxiaIndolesIonomycinMitochondriaOxygenPhospholambanSarcoplasmic Reticulum Calcium-Transporting ATPasesCalciumCalcium-Binding Proteinscyclopiazonic acidIndolesIonomycinOxygenPhospholambanSarcoplasmic Reticulum Calcium-Transporting ATPasesCa2+ overloadCa2+ signalingmitochondriaoxygenphysiological normoxia

Identifiers

PMID29273673
PMCPMC5901376
OpenAlexW2780513146

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.