Observational studyBMJ open2017
Perfusion index in healthy newborns during critical congenital heart disease screening at 24 hours: retrospective observational study from the USA.
Observational study in BMJ open, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
11 citing papers in PubMed, 25 citations in OpenAlex.
- Pulse Oximetry Screening in the Newborn: Can Modifications to the Screening Algorithm Improve Detection?International journal of neonatal screening · 2026Review
- Performing Pulse Oximetry Screening in the Delivery Room Identified Newborn Infants Who Required Early Medical Attention.Acta paediatrica (Oslo, Norway : 1992) · 2025Article
- Incorporating an Elevated Perfusion Index in the Right Hand Enhanced Screening Sensitivity for Critical Aortic Arch Obstruction in Newborn Infants.Acta paediatrica (Oslo, Norway : 1992) · 2025Article
- Normal Value of Perfusion Index in Healthy Neonates Born in Iran.Archives of Iranian medicine · 2024Article
- Distribution and reference values of peripheral perfusion index in neonates from population-wide screening.BMJ paediatrics open · 2024Article
- Machine Learning-Based Critical Congenital Heart Disease Screening Using Dual-Site Pulse Oximetry Measurements.Journal of the American Heart Association · 2024Article
- Evaluation of tissue perfusion status in moderate to late preterm.Physiological research · 2022Article
- Peripheral Saturation and Perfusion Index on the First Day of Life Play a Role in Early Discharge of Healthy Term Newborns.International journal of clinical practice · 2022Observational
- Low false-positive rate of perfusion index as a screening tool for neonatal aortic coarctation.Acta paediatrica (Oslo, Norway : 1992) · 2021Article
- Oxygen saturation and perfusion index screening in neonates at high altitudes: can PDA be predicted?European journal of pediatrics · 2021Article
- A novel system to collect dual pulse oximetry data for critical congenital heart disease screening research.Journal of clinical and translational science · 2020Article
Corrections and comments
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo describe the distribution of perfusion index (PI) in asymptomatic newborns at 24 hours of life when screening for critical congenital heart disease (CCHD) using an automated data selection method.
designThis is a retrospective observational study.
settingNewborn nursery in a California public hospital with ~3500 deliveries annually.
methodsWe developed an automated programme to select the PI values from CCHD screens. Included were term and late preterm infants who were screened for CCHD from November 2013 to January 2014 and from May 2015 to July 2015. PI measurements were downloaded every 2 s from the pulse oximeter and median PI were calculated for each oxygen saturation screen in our cohort.
resultsWe included data from 2768 oxygen saturation screens. Each screen had a median of 29 data points (IQR 17 to 49). The median PI in our study cohort was 1.8 (95% CI 1.8 to 1.9) with IQR 1.2 to 2.7. The median preductal PI was significantly higher than the median postductal (1.9 vs 1.8, p=0.03) although this difference may not be clinically significant.
conclusionUsing an automated data selection method, the median PI in asymptomatic newborns at 24 hours of life is 1.8 with a narrow IQR of 1.2 to 2.7. This automated data selection method may improve accuracy and precision compared with manual data collection method. Further studies are needed to establish external validity of this automated data selection method and its clinical application for CCHD screening.
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