Evidence map›Paper›PMID 29273633›Full record

ArticleThe Journal of biological chemistry2018

OTX1 regulates cell cycle progression of neural progenitors in the developing cerebral cortex.

Baoshan Huang, Xue Li, Xiaomeng Tu, Wei Zhao, Dan Zhu, Yue Feng, Xiang Si, Jie-Guang Chen

Open access · hybridAbstract read
In one paragraph

Article in The Journal of biological chemistry, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 1 pooled it
0.8field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 1 synthesis or guideline pooled it, 31 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Isogenic iPSC-derivedFrontiers in neuroscience · 2025
    Article
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  7. Article
  8. Review
  9. Article
  10. Article
  11. International journal of molecular sciences · 2023
    Review
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  16. Review
  17. Article
  18. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Baoshan HuangFrom the School of Ophthalmology and Optometry and Eye Hospital.
Xue LiFrom the School of Ophthalmology and Optometry and Eye Hospital.
Xiaomeng TuFrom the School of Ophthalmology and Optometry and Eye Hospital.
Wei ZhaoFrom the School of Ophthalmology and Optometry and Eye Hospital.
Dan ZhuFrom the School of Ophthalmology and Optometry and Eye Hospital.
Yue FengFrom the School of Ophthalmology and Optometry and Eye Hospital.
Xiang SiFrom the School of Ophthalmology and Optometry and Eye Hospital.
Jie-Guang ChenFrom the School of Ophthalmology and Optometry and Eye Hospital, jgchen@mail.eye.ac.cn jiesbooks@gmail.com.
Affiliated Eye Hospital of Wenzhou Medical College · CNWenzhou Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The progenitor cells in the cerebral cortex coordinate proliferation and mitotic exit to generate the correct number of neurons and glial cells during development. However, mechanisms for regulating the mitotic cycle of cortical progenitors are not fully understood.

Indexed as

Cell CycleAnimalsAstrocytesCell CountCell DifferentiationCell ProliferationCerebral CortexMiceNeural Stem CellsNeurogenesisNeuronsOtx Transcription FactorsOtx1 protein, mouseOtx Transcription Factorscell cyclecerebral cortexgene expressiongliogenesisin utero electroporationmouseneurogenesisOTX1progenitorsproliferation

Identifiers

PMID29273633
PMCPMC5808773
OpenAlexW2777782493

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.