Evidence map›Paper›PMID 29273053›Full record

ArticleMalaria journal2017

Are respiratory complications of Plasmodium vivax malaria an underestimated problem?

Fernando Val, Sara Avalos, André Alexandre Gomes, José Evelio Albornoz Zerpa, Gustavo Fontecha, André Machado Siqueira, Quique Bassat, Maria Graças Costa Alecrim, Wuelton Marcelo Monteiro, Marcus Vinícius Guimarães Lacerda

Open access · goldAbstract read
In one paragraph

Article in Malaria journal, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
2.5field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 23 citations in OpenAlex.

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  4. Epidemiological shifts: the emergence of malaria in America.Proceedings (Baylor University. Medical Center) · 2023
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  5. Review
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  7. Open forum infectious diseases · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 3 countries.

Fernando ValFundação de Medicina Tropical Dr. Heitor Vieira Dourado, Manaus, Amazonas, Brazil. ffaval@gmail.com.ORCID 0000-0001-9995-0249
Sara AvalosMicrobiology Research Institute, Universidad Nacional Autónoma de Honduras, Tegucigalpa, Honduras.
André Alexandre GomesFundação de Medicina Tropical Dr. Heitor Vieira Dourado, Manaus, Amazonas, Brazil.
José Evelio Albornoz ZerpaFundação de Medicina Tropical Dr. Heitor Vieira Dourado, Manaus, Amazonas, Brazil.
Gustavo FontechaMicrobiology Research Institute, Universidad Nacional Autónoma de Honduras, Tegucigalpa, Honduras.
André Machado SiqueiraInstituto Nacional de Infectologia Evandro Chagas, Fundação Oswaldo Cruz, Rio de Janeiro, Brazil.
Quique BassatISGlobal, Barcelona Ctr. Int. Health Res. (CRESIB), Hospital Clínic-Universitat de Barcelona, Barcelona, Spain.
Maria Graças Costa AlecrimFundação de Medicina Tropical Dr. Heitor Vieira Dourado, Manaus, Amazonas, Brazil.
Wuelton Marcelo MonteiroFundação de Medicina Tropical Dr. Heitor Vieira Dourado, Manaus, Amazonas, Brazil. wueltonmm@gmail.com.
Marcus Vinícius Guimarães LacerdaFundação de Medicina Tropical Dr. Heitor Vieira Dourado, Manaus, Amazonas, Brazil.
Fundação de Medicina Tropical · BRNational Autonomous University of Honduras · HNInstitució Catalana de Recerca i Estudis Avançats · ESInstituto Evandro Chagas · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundRespiratory complications are uncommon, but often life-threatening features of Plasmodium vivax malaria. This study aimed to estimate the prevalence and lethality associated with such complications among P. vivax malaria patients in a tertiary hospital in the Western Brazilian Amazon, and to identify variables associated with severe respiratory complications, intensive care need and death. Medical records from 2009 to 2016 were reviewed aiming to identify all patients diagnosed with P. vivax malaria and respiratory complications. Prevalence, lethality and risk factors associated with WHO defined respiratory complications, intensive care need and death were assessed.

resultsA total of 587 vivax malaria patients were hospitalized during the study period. Thirty (5.1%) developed respiratory complications. Thirteen (43.3%) developed severe respiratory complications, intensive care was required for 12 (40%) patients and 5 (16.6%) died. On admission, anaemia and thrombocytopaenia were common findings, whereas fever was unusual. Patients presented different classes of parasitaemia and six were aparasitaemic on admission. Time to respiratory complications occurred after anti-malarials administration in 18 (60%) patients and progressed very rapidly. Seventeen patients (56.7%) had comorbidities and/or concomitant conditions, which were significantly associated to higher odds of developing severe respiratory complications, need for intensive care and death (p < 0.05).

conclusionRespiratory complications were shown to be associated with significant mortality in this population. Patients with comorbidities and/or concomitant conditions require special attention to avoid this potential life-threatening complication.

Indexed as

AdultAnemiaAntimalarialsBrazilCritical CareFemaleHospitalizationHumansLungMalaria, VivaxMaleMiddle AgedParasitemiaPlasmodium vivaxPrevalenceRespiratory Distress SyndromeAntimalarialsCase fatalityLungPlasmodium vivaxPrevalenceRespiratory distressSevere malaria

Identifiers

PMID29273053
PMCPMC5741897
OpenAlexW2778822489

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.