Evidence map›Paper›PMID 29273044›Full record

Trial reportThe international journal of behavioral nutrition and physical activity2017

A randomized controlled trial of exercise during pregnancy on maternal and neonatal outcomes: results from the PAMELA study.

Shana Ginar da Silva, Pedro Curi Hallal, Marlos Rodrigues Domingues, Andréa Dâmaso Bertoldi, Mariângela Freitas da Silveira, Diego Bassani, Inácio Crochemore Mohnsam da Silva, Bruna Gonçalves Cordeiro da Silva, Carolina de Vargas Nunes Coll, Kelly Evenson

Registry-linked trialAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in The international journal of behavioral nutrition and physical activity, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02148965 (Effects of Exercise During Pregnancy on Maternal and Child Health), which is not on this map. Cited by 55 papers, 18 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
55citing papers in PubMed, 18 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02148965 nacompletednot on this map

Effects of Exercise During Pregnancy on Maternal and Child Health: a Randomized Clinical Trial

TypeinterventionalSponsorFederal University of PelotasRan2014 to 2016Enrolled639ConditionsGestational Hypertension, Prematurity, Maternal Post-partum Depression, Maternal Post-partum Weight RetentionArmsPhysical Exercise / Physical Activity
3 · Its place in the literature

Who cites it

55 citing papers in PubMed, 18 syntheses or guidelines pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Shana Ginar da SilvaPostgraduate Program in Epidemiology, Federal University of Pelotas, Rua Marechal Deodoro, 1160-3° piso, CEP: 96020-220, Bairro Centro, Pelotas, Rio Grande do Sul, Brazil. sginar@gmail.com.
Pedro Curi HallalPostgraduate Program in Epidemiology, Federal University of Pelotas, Rua Marechal Deodoro, 1160-3° piso, CEP: 96020-220, Bairro Centro, Pelotas, Rio Grande do Sul, Brazil.
Marlos Rodrigues DominguesPostgraduate Program in Physical Education, Federal University of Pelotas, Pelotas, Brazil.
Andréa Dâmaso BertoldiPostgraduate Program in Epidemiology, Federal University of Pelotas, Rua Marechal Deodoro, 1160-3° piso, CEP: 96020-220, Bairro Centro, Pelotas, Rio Grande do Sul, Brazil.
Mariângela Freitas da SilveiraPostgraduate Program in Epidemiology, Federal University of Pelotas, Rua Marechal Deodoro, 1160-3° piso, CEP: 96020-220, Bairro Centro, Pelotas, Rio Grande do Sul, Brazil.
Diego BassaniDepartment of Paediatrics, Faculty of Medicine, Centre for Global Child Health, University of Toronto; King's College Circle, The Hospital for Sick Children, Toronto, Canada.
Inácio Crochemore Mohnsam da SilvaPostgraduate Program in Epidemiology, Federal University of Pelotas, Rua Marechal Deodoro, 1160-3° piso, CEP: 96020-220, Bairro Centro, Pelotas, Rio Grande do Sul, Brazil.
Bruna Gonçalves Cordeiro da SilvaPostgraduate Program in Epidemiology, Federal University of Pelotas, Rua Marechal Deodoro, 1160-3° piso, CEP: 96020-220, Bairro Centro, Pelotas, Rio Grande do Sul, Brazil.
Carolina de Vargas Nunes CollPostgraduate Program in Epidemiology, Federal University of Pelotas, Rua Marechal Deodoro, 1160-3° piso, CEP: 96020-220, Bairro Centro, Pelotas, Rio Grande do Sul, Brazil.
Kelly EvensonDepartment of Epidemiology, Gillings School of Global Public Health, University of North Carolina - Chapel Hill, Chapel Hill, NC, USA.

Funding

Wellcome Trust 095582/z/11/z
6 · The paper itself

Abstract

backgroundWomen are encouraged to be physically active during pregnancy. Despite available evidence supporting antenatal physical activity to bring health benefits for both the mother and child, the most effective way to prevent some maternal and fetal outcomes is still unclear. The purpose of this study was to evaluate the efficacy of an exercise intervention to prevent negative maternal and newborn health outcomes.

methodsA randomized controlled trial (RCT) nested into the 2015 Pelotas (Brazil) Birth Cohort Study was carried-out with 639 healthy pregnant women, 213 in the intervention group (IG) and 426 in the control (CG) group. An exercise-based intervention was conducted three times/week for 16 weeks from 16-20 to 32-36 weeks' gestation. The main outcomes were preterm birth and pre-eclampsia. Gestational age was calculated based on several parameters, including routine ultrassounds and/or last menstrual period and categorized as < 37 weeks and ≥ 37 weeks for evaluation of preterm birth. Pre-eclampsia was self-reported. Secondary outcomes were gestational weight gain, gestational diabetes, birth weight, infant length, and head circumference. Analyses were performed by intention-to-treat (ITT) and per protocol (70% of the 48 planned exercise sessions). Odds ratio were derived using unconditional logistic regression.

resultsThe IG and CG did not differ at baseline regarding their mean age (27.2 years ± 5.3 vs. 27.1 years ± 5.7) and mean pre-pregnancy body mass index (25.1 ± 3.9 vs. 25.2 ± 4.1 kg/m

conclusionsWhile the RCT did not support the benefits of exercise performed during pregnancy on preeclampsia and preterm birth, the exercise program also did not present adverse impacts on newborn health. Our findings may contribute to promote intervention strategies that motivate health providers to encourage pregnant women to be more physically active.

trial registrationClinicaltrials.gov identifier: NCT02148965 , registered on 22 May 2014.

Indexed as

ExercisePregnancy OutcomeAdultBirth WeightBody Mass IndexBrazilCohort StudiesDiabetes, GestationalFemaleGestational AgeHumansIncidenceInfantPatient CompliancePre-EclampsiaPregnancyExerciseIntervention studiesMaternal-child healthPhysical activityPregnant womanRandomized controlled trial

Identifiers

PMID29273044
PMCPMC5741924

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.