ArticleJournal of the National Cancer Institute2018
Validation of the Symptom Screening in Pediatrics Tool in Children Receiving Cancer Treatments.
Article in Journal of the National Cancer Institute, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 3 registered trials, which are not on this map. Cited by 58 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Symptom Screening Linked to Care Pathways for Children With Cancer: a Cluster Randomized Trial
A Randomized Controlled Trial a Dyad Approach to Symptom Screening (Co-SSPedi) vs. Proxy-report (Proxy-SSPedi) and Self-report (SSPedi or Mini-SSPedi) for Pediatric Patients Receiving Cancer Treatments
Feasibility of Medically Tailored Meals for Pediatric Populations at Risk for Disparities in Serious Illness Outcomes Due to Inequities in Social Drivers of Health (MTM-Kids)
Who cites it
58 citing papers in PubMed, 3 syntheses or guidelines pooled it, 112 citations in OpenAlex.
- Pain assessment tools in paediatric palliative care: A systematic review of psychometric properties and recommendations for clinical practice.Palliative medicine · 2022Pooled it
- Identifying clinical practice guidelines for the supportive care of children with cancer: A report from the Children's Oncology Group.Pediatric blood & cancer · 2019Pooled it
- Perspectives of children, family caregivers, and health professionals about pediatric oncology symptoms: a systematic review.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2018Pooled it
- Factors Associated With Symptom Burden Among Pediatric Patients With Cancer.JCO oncology practice · 2026Trial
- Factors Associated With Self-Report Symptom Screening Adherence in Pediatric Cancer Patients.Cancer medicine · 2025Trial
- Symptom management care pathway adaptation process and specific adaptation decisions.BMC cancer · 2023Trial
- Barriers to symptom management care pathway implementation in pediatric Cancer.BMC health services research · 2021Trial
- Implementation of a universal psychosocial screening program across the pediatric cancer treatment trajectory: a standard of care.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026Article
- Multi-Center Evaluation of Opioid Administration or Prescription in Pediatric Oncology Patients Using the OMOP CDM.Cancer medicine · 2026Observational
- Scaling up symptom screening for routine use in pediatric oncology: provincial implementation.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026Article
- Observational
- The Use of Patient-Reported Outcome Measures in Paediatric Haematopoietic Stem Cell Transplant: A Systematic Review.Children (Basel, Switzerland) · 2026Review
- Care Pathway- and Guideline-Consistent Care in Pediatric Cancer Symptom Management.JCO oncology practice · 2026Article
- Development and prospective evaluation of a machine learning model to predict vomiting among pediatric cancer and hematopoietic cell transplant patients.BMC cancer · 2025Article
- Defining and measuring tolerability in pediatric, adolescent, and young adult oncology: The essential voices.Cancer · 2025Review
- Development of an electronic system for self/proxy symptom tracking alongside children with cancer and their caregivers: a co-design exemplar.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2025Article
- Do Not Throw Away Your Patient's Shot at Complete Vomiting Control.The journal of pediatric pharmacology and therapeutics : JPPT : the official journal of PPAG · 2025Article
- Management of fatigue in children with cancer: a survey of pediatric hematology-oncology professionals' knowledge, attitudes, and practices in the United States and Canada.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2025Article
- Symptom Documentation in Unstructured Palliative Care Notes of Children and Adolescents With Cancer.Journal of pain and symptom management · 2025Article
- Language understanding and preferences when reporting symptoms for pediatric patients receiving cancer treatments and their guardians.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
15 authors at 12 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: The objective was to evaluate the reliability and validity of the self-report Symptom Screening in Pediatrics Tool (SSPedi) from the perspective of children with cancer and pediatric hematopoietic stem cell transplant (HSCT) recipients. Methods: In this multicenter study, respondents were children age eight to 18 years who had cancer or had received HSCT, and their parents. Two different child respondent populations were targeted. More symptomatic respondents were receiving active treatment for cancer, admitted to the hospital, and expected to be in the hospital three days later. Less symptomatic respondents were in maintenance therapy for acute lymphoblastic leukemia or had completed cancer therapy. Children completed SSPedi and then responded to validated self-report measures of mucositis, nausea, pain, and global quality of life. Children in the more symptomatic group repeated SSPedi and a global symptom change scale three days later. Parent proxy-report was optional. Reliability was evaluated using intraclass correlations while convergent validity was evaluated using Spearman correlations. Results: Of 502 children enrolled, 302 were in the more symptomatic group and 200 were in the less symptomatic group. Intraclass correlation coefficients were 0.88 (95% confidence interval [CI] = 0.82 to 0.92) for test-retest reliability and 0.76 (95% CI = 0.71 to 0.80) for inter-rater reliability. The mean difference in SSPedi scores between more and less symptomatic groups was 7.8 (95% CI = 6.4 to 9.2). SSPedi was responsive to change in global symptoms. All hypothesized relationships among measures were observed. Conclusions: SSPedi is a self-report symptom bother tool for children with cancer and HSCT recipients that is reliable, valid, and responsive to change. SSPedi can be used for clinical and research purposes. Future work should focus on integration into care delivery.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.