Evidence map›Paper›PMID 29271879›Full record

ArticleInternational journal of molecular sciences2017

Assessing the Effectiveness of a Far-Red Fluorescent Reporter for Tracking Stem Cells In Vivo.

Jing Zhou, Jack Sharkey, Rajeev Shukla, Antonius Plagge, Patricia Murray

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Non-invasive Reporter Gene Imaging of Cell Therapies, including T Cells and Stem Cells.Molecular therapy : the journal of the American Society of Gene Therapy · 2020
    Review
  3. How Non-invasiveFrontiers in physiology · 2020
    Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Jing ZhouInstitute of Translational Medicine, University of Liverpool, Liverpool L69 3BX, UK. J.Zhou18@liverpool.ac.uk.
Jack SharkeyInstitute of Translational Medicine, University of Liverpool, Liverpool L69 3BX, UK. J.Sharkey@liverpool.ac.uk.
Rajeev ShuklaAlder Hey Children's NHS Foundation Trust, Liverpool L12 2AP, UK. Rajeev.Shukla@alderhey.nhs.uk.
Antonius PlaggeInstitute of Translational Medicine, University of Liverpool, Liverpool L69 3BX, UK. A.Plagge@liverpool.ac.uk.
Patricia MurrayInstitute of Translational Medicine, University of Liverpool, Liverpool L69 3BX, UK. P.A.Murray@liverpool.ac.uk.

Funding

Medical Research Council MR/K026739/1Medical Research Council MR/L012707/1
6 · The paper itself

Abstract

Far-red fluorescent reporter genes can be used for tracking cells non-invasively in vivo using fluorescence imaging. Here, we investigate the effectiveness of the far-red fluorescent protein, E2-Crimson (E2C), for tracking mouse embryonic cells (mESCs) in vivo following subcutaneous administration into mice. Using a knock-in strategy, we introduced

Indexed as

AnimalsCell TrackingFemaleFluorescent DyesGene Knock-In TechniquesLuminescent ProteinsMiceMice, SCIDMouse Embryonic Stem CellsNeoplasmsOptical ImagingRed Fluorescent ProteinTransgenesFluorescent DyesLuminescent ProteinsRed Fluorescent ProteinE2-Crimsonfluorescent reporterin vivo imagingknock-inmouse embryonic stem cells

Identifiers

PMID29271879
PMCPMC5795970

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.