Evidence map›Paper›PMID 29271299›Full record

ArticleMolecular imaging

Contrast-Enhanced Near-Infrared Optical Imaging Detects Exacerbation and Amelioration of Murine Muscular Dystrophy.

Stephen M Chrzanowski, Ravneet S Vohra, Brittany A Lee-McMullen, Abhinandan Batra, Ray A Spradlin, Jazmine Morales, Sean Forbes, Krista Vandenborne, Elisabeth R Barton, Glenn A Walter

Open access · goldAbstract readComparative Study
PubMed Full text at PMC Publisher
In one paragraph

Article in Molecular imaging. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Skeletal muscle in health and disease.Disease models & mechanisms · 2020
    Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Stephen M Chrzanowski1 Department of Physiology and Functional Genomics, University of Florida, Gainesville, FL, USA.
Ravneet S Vohra1 Department of Physiology and Functional Genomics, University of Florida, Gainesville, FL, USA.
Brittany A Lee-McMullen2 Department of Biochemistry, University of Florida, Gainesville, FL, USA.
Abhinandan Batra3 Department of Physical Therapy, University of Florida, Gainesville, FL, USA.
Ray A Spradlin4 Department of Applied Physiology and Kinesiology, University of Florida, Gainesville, FL, USA.
Jazmine Morales4 Department of Applied Physiology and Kinesiology, University of Florida, Gainesville, FL, USA.
Sean Forbes3 Department of Physical Therapy, University of Florida, Gainesville, FL, USA.
Krista Vandenborne3 Department of Physical Therapy, University of Florida, Gainesville, FL, USA.
Elisabeth R Barton4 Department of Applied Physiology and Kinesiology, University of Florida, Gainesville, FL, USA.
Glenn A Walter1 Department of Physiology and Functional Genomics, University of Florida, Gainesville, FL, USA.
University of Florida · USUniversity of Florida Health · US

Funding

Training In Rehabilitation and Neuromuscular PlasticityT32HD043730 · NICHD · UNIVERSITY OF FLORIDA · PI DAVID D FULLER · 2003 to 2026
$5.3M
Multidisciplinary Training Program in HypertensionT32HL083810 · NHLBI · UNIVERSITY OF FLORIDA · PI WOOD, CHARLES E · 2007 to 2017
$2.5M
NHLBI NIH HHS T32 HL083810NICHD NIH HHS T32 HD043730
6 · The paper itself

Abstract

Assessment of muscle pathology is a key outcome measure to measure the success of clinical trials studying muscular dystrophies; however, few robust minimally invasive measures exist. Indocyanine green (ICG)-enhanced near-infrared (NIR) optical imaging offers an objective, minimally invasive, and longitudinal modality that can quantify pathology within muscle by imaging uptake of ICG into the damaged muscles. Dystrophic mice lacking dystrophin (mdx) or gamma-sarcoglycan (Sgcg

Indexed as

AnimalsContrast MediaDisease Models, AnimalDystrophinGenetic TherapyGenetic VectorsHumansMagnetic Resonance ImagingMiceMice, Inbred mdxMuscle, SkeletalMuscular DystrophiesOptical ImagingSarcoglycansContrast MediaDystrophinSarcoglycansSGCG protein, humanadeno-associated virusmuscular dystrophynear-infrared optical imaging

Identifiers

PMID29271299
PMCPMC5985549
OpenAlexW2779059315

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.