ArticleInternational urogynecology journal2018
Detrusor underactivity in pelvic organ prolapse.
Article in International urogynecology journal, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04184128 (Prevalence of Detrusor Underactivity and Bladder Outlet Obstruction in Women With Cystocele and Changes of Voiding Function After Cystocele), which is not on this map. Cited by 22 papers.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Prevalence of Detrusor Underactivity and Bladder Outlet Obstruction in Women With Cystocele and Changes of Voiding Function After Cystocele
Who cites it
22 citing papers in PubMed, 47 citations in OpenAlex.
- Trial
- Is There a Role for Urodynamic Investigation in the Management of Pelvic Organ Prolapse?Journal of clinical medicine · 2025Review
- The Role of Anterior Vaginal Prolapse in Co-Existent Underactive Overactive Bladder Syndrome-A Retrospective Cohort Study.Journal of clinical medicine · 2025Article
- Correlation Between Apical, Anterior, and Posterior Vaginal Wall Prolapse With Voiding Dysfunction: A Single Center Retrospective Cohort Study.Journal of family & reproductive health · 2024Article
- Does vaginal surgery for correction of pelvic organ prolapse improve urinary function? A prospective cohort study.International urogynecology journal · 2024Article
- Detrusor underactivity in symptomatic anterior pelvic organ prolapse.Central European journal of urology · 2024Article
- Flat Magnetic Stimulation for Urge Urinary Incontinence.Medicina (Kaunas, Lithuania) · 2023Article
- International Urogynecology consultation chapter 2 committee 3: the clinical evaluation of pelvic organ prolapse including investigations into associated morbidity/pelvic floor dysfunction.International urogynecology journal · 2023Review
- The effect of prolapse surgery on voiding function.International urogynecology journal · 2023Observational
- Detrusor-Overactivity-Related Voiding in Women Mimics Bladder Outflow Obstruction and Conceals Underactivity.Urology research & practice · 2023Article
- Predictors of persistent overactive bladder following surgery for advanced pelvic organ prolapse.International urogynecology journal · 2023Article
- Coexisting overactive-underactive bladder and detrusor overactivity-underactivity in pelvic organ prolapse.International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics · 2023Article
- Coexistent Detrusor Overactivity-Underactivity in Patients with Pelvic Floor Disorders.Healthcare (Basel, Switzerland) · 2022Article
- Native Tissue Posterior Compartment Repair for Isolated Posterior Vaginal Prolapse: Anatomical and Functional Outcomes.Medicina (Kaunas, Lithuania) · 2022Article
- Detrusor underactivity prevalence and risk factors according to different definitions in women attending urogynecology clinic.International urogynecology journal · 2022Article
- Update in fertility-sparing native-tissue procedures for pelvic organ prolapse.International urogynecology journal · 2020Article
- Transvaginal uterosacral ligament hysteropexy versus hysterectomy plus uterosacral ligament suspension: a matched cohort study.International urogynecology journal · 2020Article
- Impact of preoperative urodynamics on women undergoing pelvic organ prolapse surgery.International urogynecology journal · 2020Article
- Systematic review of lower urinary tract symptoms occurring with pelvic organ prolapse.Arab journal of urology · 2019Review
- Management of Postoperative Lower Urinary Tract Symptoms (LUTS) After Pelvic Organ Prolapse (POP) Repair.Current urology reports · 2018Review
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introduction and hypothesisThe association between pelvic organ prolapse (POP) and detrusor underactivity (DU) is not well defined. The primary outcome of this study was to evaluate the prevalence of DU in a cohort of patients with POP and its association with symptoms, anatomy. and urodynamic findings. The secondary outcome was to evaluate the evolution of lower urinary tract symptoms after POP repair between DU and non-DU patients.
methodsConsecutive patients who underwent preoperative urodynamic tests were retrospectively analyzed. Detrusor underactivity was evaluated by the Bladder Contractility Index (BCI = pDetQmax + Qmax × 5) proposed by Abrams. A BCI < 100 was considered indicative of an underactive bladder. Patients with underactive bladder were considered group A, whereas the remaining patients were classified as group B.
resultsA total of 518 patients were studied. According to BCI, detrusor underactivity was identified in 212 (40.9%) patients (group A). Group A showed higher rates of voiding symptoms (59.4% vs 36.3%, p < 0.0001) and positive (>100 ml) postvoid residual (29.7% vs 9.8%, p < 0.0001). Conversely, they displayed lower rates of urge incontinence (15.1% vs 23.2%, p = 0.02) and detrusor overactivity (15.6% vs 23.9%, p = 0.02). Preoperative Pelvic Organ Prolapse Quantification (POP-Q) demonstrated greater Aa (+1.1 ± 1.5 vs +0.9 ± 1.5, p = 0.03) and Ba (+1.4 ± 1.7 vs +1.2 ± 1.7, p = 0.04) points values in patients in group A. After POP surgery, postoperative voiding symptoms were similar in the two groups (16% vs 15.7%, p = 0.91).
conclusionsOur study showed a 40.9% prevalence of DU in POP patients. DU was associated with the presence of voiding symptoms and positive PVR. Moreover, cystocele showed to be more severe in DU group. After surgical repair of POP, voiding symptoms of DU patients became equal to non-DU ones, suggesting that obstruction removal might recover DU in these patients.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.