Evidence map›Paper›PMID 29270642›Full record

ArticleRheumatology international2018

The associations between radiographic hand osteoarthritis definitions and hand pain: data from the osteoarthritis initiative.

Lena F Schaefer, Timothy E McAlindon, Charles B Eaton, Mary B Roberts, Ida K Haugen, Stacy E Smith, Jeffrey Duryea, Jeffrey B Driban

Open access · greenAbstract readComparative Study
PubMed Full text at PMC Publisher
In one paragraph

Article in Rheumatology international, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 1 pooled it
1.3field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 1 synthesis or guideline pooled it, 23 citations in OpenAlex.

  1. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 2 countries.

Lena F SchaeferDepartment of Radiology, Brigham and Women's Hospital, Harvard Medical School, 75 Francis Street, Boston, MA, 02115, USA. lenafranziskaschaefer@yahoo.com.
Timothy E McAlindonDivision of Rheumatology, Tufts Medical Center, Boston, USA.
Charles B EatonCenter for Primary Care, Prevention, Alpert Medical School of Brown University, Providence, USA.
Mary B RobertsCenter for Primary Care, Prevention, Alpert Medical School of Brown University, Providence, USA.
Ida K HaugenDepartment of Rheumatology, Diakonhjemmet Hospital, Oslo, Norway.
Stacy E SmithDepartment of Radiology, Brigham and Women's Hospital, Harvard Medical School, 75 Francis Street, Boston, MA, 02115, USA.
Jeffrey DuryeaDepartment of Radiology, Brigham and Women's Hospital, Harvard Medical School, 75 Francis Street, Boston, MA, 02115, USA.
Jeffrey B DribanDivision of Rheumatology, Tufts Medical Center, Boston, USA.
Brown University · USHarvard University · USTufts Medical Center · USBrigham and Women's Hospital · USDiakonhjemmet Hospital · NO

Funding

Constitutional and metabolic factors associated with the development of Hand OAR01AR066378 · NIAMS · TUFTS MEDICAL CENTER · PI MCALINDON, TIMOTHY E · 2015 to 2018
$2.6M
National Institute of Arthritis and Musculoskeletal and Skin Diseases R01-AR066378NIAMS NIH HHS R01 AR066378
6 · The paper itself

Abstract

The goal of our study was to evaluate the associations between various definitions of radiographic hand osteoarthritis (OA) and self-reported hand pain. We conducted a cross-sectional study with 3604 participants from the Osteoarthritis Initiative (OAI). Posteroanterior radiographs of the dominant hand were read using a modified Kellgren-Lawrence (KL) scale. For our primary analysis, hand OA at person level was defined as two or more finger joints with KL grade 2 or higher. In addition, for the purpose of exploratory analyses, we explored more conservative definitions of hand OA as well as different sum scores and digit- and row-based scores. The majority of definitions of radiographic hand OA were statistically significantly associated with self-reported hand pain. In our main analysis, persons with two or more finger joints with KL grade > 2 were approximately two times more likely to self-report hand pain than persons without radiographic hand OA. Increasing KL grades and increasing number of joints affected lead to stronger associations. Almost all definitions of hand OA were related to pain. Individuals with more severely affected joints or with higher number of affected joints are more likely to report hand pain than their peers. Specifically, individuals with hand joints with KL 3 or 4 have the greatest likelihood of hand pain.

Indexed as

Pain MeasurementAgedArea Under CurveArthralgiaCross-Sectional StudiesFemaleHand JointsHumansMaleMiddle AgedOsteoarthritisPredictive Value of TestsReproducibility of ResultsRisk FactorsROC CurveSelf ReportHand osteoarthritisPainRadiograph

Identifiers

PMID29270642
PMCPMC5823747
OpenAlexW2778608684

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.