Evidence map›Paper›PMID 29270567›Full record

ArticleNorthern clinics of Istanbul2017

Evaluation of the wound healing potential of Aloe vera-based extract of Nerium oleander.

Sevcan Gul Akgun, Sezgin Aydemir, Naziye Ozkan, Meral Yuksel, Semra Sardas

Open access · diamondAbstract read
In one paragraph

Article in Northern clinics of Istanbul, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
1.1field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it, 15 citations in OpenAlex.

  1. A critical overview of challenging roles of medicinal plants in improvement of wound healing technology.Daru : journal of Faculty of Pharmacy, Tehran University of Medical Sciences · 2024
    Pooled it
  2. Article
  3. Review
  4. Efficacy ofAdvances in pharmacological sciences · 2018
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Sevcan Gul AkgunDepartment of Pharmaceutical Toxicology, Faculty of Pharmacy, Marmara University, Istanbul, Turkey.
Sezgin AydemirDepartment of Pathology Laboratory Technicianship, Vocational School of Health Related Services, Marmara University, Istanbul, Turkey.
Naziye OzkanDepartment of Pathology Laboratory Technicianship, Vocational School of Health Related Services, Marmara University, Istanbul, Turkey.
Meral YukselDepartment of Medical Laboratory Technicianship, Vocational School of Health Related Services, Marmara University, Istanbul, Turkey.
Semra SardasDepartment of Pharmaceutical Toxicology, Faculty of Pharmacy, Marmara University, Istanbul, Turkey.
Marmara University · TR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveNerium oleander (Apocynaceae) and Aloe vera (Liliaceae) are among the widely used herbal remedies for treating skin diseases and possess numerous activities such as antibacterial, antiviral, antifungal, and antioxidant. The aim of this study was to investigate the possible wound healing effect of Aloev era-based extract of the N. oleander leaf (NAE-8

methodsTwenty-four Wistar albino rats were randomly grouped as follows: i) control, ii) burn alone (burn), iii) burn with topical NAE-8

resultsThermal injury-induced alterations in MDA, GSH, MPO, TNF-α, IL-1β, and %DNAT levels were significantly reversed by NAE-8

conclusionFindings of the present study suggest that NAE-8

Indexed as

Anti-inflammatory effectantioxidant effectDNA damagenerium oleander

Identifiers

PMID29270567
PMCPMC5724913
OpenAlexW2745528526

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.