ArticleKidney international reports2017
Polymorphisms in Renal Ammonia Metabolism Genes Correlate With 24-Hour Urine pH.
Article in Kidney international reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
8 citing papers in PubMed, 11 citations in OpenAlex.
- Hyperuricemia increases susceptibility to chronic kidney injury exacerbation via autophagic flux blockade-mediated ammonia death pathway.Journal of advanced research · 2026Article
- Multi-tissue gene expression profiling of cows with a genetic predisposition for low and high milk urea levels.Animal biotechnology · 2024Article
- State of knowledge on ammonia handling by the kidney.Pflugers Archiv : European journal of physiology · 2024Review
- Urine pH and imaging findings of prostate useful predictors of prolonged duration of hematospermia.Translational andrology and urology · 2023Article
- Structural variants in the Chinese population and their impact on phenotypes, diseases and population adaptation.Nature communications · 2021Article
- Genetics of kidney stone disease.Nature reviews. Urology · 2020Review
- Predictors of Net Acid Excretion in the Chronic Renal Insufficiency Cohort (CRIC) Study.American journal of kidney diseases : the official journal of the National Kidney Foundation · 2019Article
- Empiric therapy for kidney stones.Urolithiasis · 2019Review
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Authors and funding
10 authors at 5 institutions in 1 country.
Funding
Abstract
introductionUrine pH is critical for net acid and solute excretion, but the genetic factors that contribute to its regulation are incompletely understood.
methodsWe tested the association of single nucleotide polymorphisms (SNPs) from 16 genes related to ammonia (NH
resultsOf 2871 total SNPs in these genes, 13 SNPs in DISCUSSION: Overall, these findings suggest that variants in common genes involved in ammonia metabolism may substantively contribute to basal urine pH regulation. These variations might influence the likelihood of developing disease conditions associated with altered urine pH, such as uric acid or calcium phosphate kidney stones.
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