Evidence map›Paper›PMID 29270513›Full record

ArticleKidney international reports2017

Urinary Stone Disease and Cardiovascular Disease Risk in a Rural Chinese Population.

Xiaohong Fan, Sahir Kalim, Wenling Ye, Sophia Zhao, Jie Ma, Sagar U Nigwekar, Kevin E Chan, Jie Cui, Jianfang Cai, Liang Wang and 10 more

Open access · goldAbstract read
In one paragraph

Article in Kidney international reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
0.8field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 16 citations in OpenAlex.

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  12. A Retrospective Study of Kidney Stone Recurrence in Adults.Journal of clinical medicine research · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors at 5 institutions in 2 countries.

Xiaohong FanDepartment of Nephrology, Peking Union Medical College Hospital, Beijing, China.
Sahir KalimDepartment of Nephrology, Massachusetts General Hospital, Boston, Massachusetts, USA.
Wenling YeDepartment of Nephrology, Peking Union Medical College Hospital, Beijing, China.
Sophia ZhaoDepartment of Nephrology, Massachusetts General Hospital, Boston, Massachusetts, USA.
Jie MaDepartment of Nephrology, Peking Union Medical College Hospital, Beijing, China.
Sagar U NigwekarDepartment of Nephrology, Massachusetts General Hospital, Boston, Massachusetts, USA.
Kevin E ChanDepartment of Nephrology, Massachusetts General Hospital, Boston, Massachusetts, USA.
Jie CuiDepartment of Nephrology, Massachusetts General Hospital, Boston, Massachusetts, USA.
Jianfang CaiDepartment of Nephrology, Peking Union Medical College Hospital, Beijing, China.
Liang WangDepartment of Ultrasound, Peking Union Medical College Hospital, Beijing, China.
Wei HengDepartment of Ultrasound, the First People's Hospital of Akesu District, Xinjiang, China.
Yali ZhouDepartment of Ultrasound, the Affiliated Hospital of Jining Medical University, Jining, China.
Ying SunDepartment of Nephrology, Peking Union Medical College Hospital, Beijing, China.
Rui CuiDepartment of Nephrology, Peking Union Medical College Hospital, Beijing, China.
Wei ZhangDepartment of Nephrology, Peking Union Medical College Hospital, Beijing, China.
Baobao WangDepartment of Nephrology, Peking Union Medical College Hospital, Beijing, China.
Qing DaiDepartment of Ultrasound, Peking Union Medical College Hospital, Beijing, China.
Xuewang LiDepartment of Nephrology, Peking Union Medical College Hospital, Beijing, China.
Ravi ThadhaniDepartment of Nephrology, Massachusetts General Hospital, Boston, Massachusetts, USA.
Xuemei LiDepartment of Nephrology, Peking Union Medical College Hospital, Beijing, China.
Peking Union Medical College Hospital · CNMassachusetts General Hospital · USChinese Academy of Medical Sciences & Peking Union Medical College · CNAffiliated Hospital of Jining Medical University · CNPeople's Hospital of Xinjiang Uygur Autonomous Region · CN

Funding

The effects of protein carbamylation in end stage kidney diseaseK23DK106479 · NIDDK · MASSACHUSETTS GENERAL HOSPITAL · PI KALIM, SAHIR · 2015 to 2019
$789k
NIDDK NIH HHS K23 DK106479
6 · The paper itself

Abstract

introductionUrinary stone disease (USD) is associated with cardiovascular disease (CVD) in Western populations. However, the prevalence and relationship between USD and CVD risk have not been fully examined in the Chinese population.

methodsWe performed a cross-sectional study of 10,281 participants in rural China. All subjects underwent renal ultrasound to detect USD, brachial-ankle pulsewave velocity (baPWV) measurement to estimate arterial stiffness, and ankle-brachial index (ABI) examination to detect peripheral arterial disease (PAD) (defined as ABI <0.9 on at least 1 side of the body).

resultsMean age of the study population was 55.4 ± 10.0 years; 47.1% were men. Among all participants, 5.7% (n = 582) had USD, mean baPWV was 15.6 ± 3.2 m/s, and 4.0% had PAD. The prevalence of USD increased in parallel with mean arterial pressure, albuminuria, Framingham risk score, and baPWV. In multivariate analyses after adjustment for demographic characteristics, USD was significantly associated with an increased risk of hypertension (odds ratio [OR]: 1.32; 95% confidence interval [CI]: 1.08-1.62), albuminuria (OR: 2.17; 95% CI: 1.74-2.69), chronic kidney disease (OR: 2.11; 95% CI: 1.70-2.62), increased arterial stiffness (OR: 1.24; 95% CI: 1.01-1.52), and PAD (OR: 1.50; 95% CI: 1.04-2.16). DISCUSSION: In rural China, USD was associated with a high prevalence of traditional CVD risk factors, increased arterial stiffness, and PAD. The presence of USD should increase physician awareness of the concomitant presence of CVD risk factors.

Indexed as

arterial stiffnesscardiovascular riskchronic kidney diseasehypertensionperipheral arterial diseaseurinary stone disease

Identifiers

PMID29270513
PMCPMC5733875
OpenAlexW2622751727

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.