ArticleKidney international reports2017
Feasibility of Incremental 2-Times Weekly Hemodialysis in Incident Patients With Residual Kidney Function.
Article in Kidney international reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03740048 (A Randomized Pilot Study of Hemodialysis Initiation Comparing Twice-Weekly Hemodialysis Plus Dialysis-Sparing Therapy Versus Thrice-Weekly Hemodialysis), which is not on this map. Cited by 20 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
A Randomized Pilot Study of Hemodialysis Initiation Comparing Twice-Weekly Hemodialysis Plus Dialysis-Sparing Therapy Versus Thrice-Weekly Hemodialysis (The TWOPLUS-HD Trial)
Who cites it
20 citing papers in PubMed.
- Trial
- Article
- Vascular access in incremental hemodialysis: is less always more?Journal of nephrology · 2024Article
- Article
- Incremental and Personalized Hemodialysis Start: A New Standard of Care.Kidney international reports · 2022Article
- Incremental Hemodialysis: What We Know so Far.International journal of nephrology and renovascular disease · 2022Review
- Precision medicine in transplantation and hemodialysis.Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association · 2021Article
- Cerebral Perfusion in Hemodialysis Patients: A Feasibility Study.Canadian journal of kidney health and disease · 2021Article
- Incremental and Twice-Weekly Hemodialysis Program in Practice.Clinical journal of the American Society of Nephrology : CJASN · 2020Article
- Individualized acute kidney injury after care.Current opinion in critical care · 2020Review
- Intradialytic Nutrition and Hemodialysis Prescriptions: A Personalized Stepwise Approach.Nutrients · 2020Review
- Development of a framework for minimum and optimal safety and quality standards for hemodialysis and peritoneal dialysis.Kidney international supplements · 2020Review
- Narrative Review of Incremental Hemodialysis.Kidney international reports · 2020Review
- Dialysis Reimbursement: What Impact Do Different Models Have on Clinical Choices?Journal of clinical medicine · 2019Article
- Twice-Weekly Hemodialysis and Clinical Outcomes in the China Dialysis Outcomes and Practice Patterns Study.Kidney international reports · 2018Article
- Infrequent Dialysis: A Different Strategy to Incremental Dialysis.Kidney international reports · 2018Article
- The Authors Reply.Kidney international reports · 2018Article
- Dialysis Should Be Started When Absolutely Necessary, Not Early and Incrementally.Kidney international reports · 2018Article
- Incremental and Once- to Twice-Weekly Hemodialysis: From Experience to Evidence.Kidney international reports · 2017Article
- Estimating Residual Native Kidney Urea Clearance in Hemodialysis Patients with and without 24-Hour Urine Volume.Kidney medicineArticle
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionWe hypothesized that at least half of incident hemodialysis (HD) patients on 3-times weekly dialysis could safely start on an incremental, 2-times weekly HD schedule if residual kidney function (RKF) had been considered.
methodsRKF is assessed in all our HD patients. This single-center, retrospective cohort study of incident adult HD patients, who survived ≥6 months on a 3-times weekly HD regimen and had a timed urine collection within 3 months of starting HD, assessed each patient's theoretical ability to achieve adequate urea clearance, ultrafiltration rate, and hemodynamic stability if on 2-times weekly HD.
resultsOf the 410 patients in the cohort, we found that 112 (27%) could have optimally and 107 (26%) could have been appropriately considered for 2-times weekly incremental HD. In general, diuretics were underutilized in >50% of subjects who had adequate RKF urea clearance. The optimal 2-times weekly patients had better potassium and phosphorus control. The correlation coefficient of calculated residual kidney urea clearance with 24-hour urine volume and with kinetic model residual kidney clearance was 0.68 and 0.99, respectively. DISCUSSION: More than 50% of incident HD patients with RKF have adequate kidney urea clearance to be considered for 2-times weekly HD. When additionally ultrafiltration volume and blood pressure stability are taken into account, more than one-fourth of the total cohort could optimally start HD in an incremental fashion.
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