Evidence map›Paper›PMID 29270497›Full record

ArticleKidney international reports2017

Autosomal Dominant Polycystic Kidney Patients May Be Predisposed to Various Cardiomyopathies.

Fouad T Chebib, Marie C Hogan, Ziad M El-Zoghby, Maria V Irazabal, Sarah R Senum, Christina M Heyer, Charles D Madsen, Emilie Cornec-Le Gall, Atta Behfar, Peter C Harris and 1 more

Open access · goldAbstract read
In one paragraph

Article in Kidney international reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed
0.4field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 8 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
  4. Review
  5. Cardiovascular Complications in ADPKD.Kidney international reports · 2025
    Review
  6. Review
  7. Article
  8. Article
  9. Autosomal Dominant Polycystic Kidney Disease: Extrarenal Involvement.International journal of molecular sciences · 2024
    Review
  10. Review
  11. Cardiovascular Manifestations and Management in ADPKD.Kidney international reports · 2023
    Review
  12. Article
  13. Review
  14. Article
  15. Review
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 1 institution in 1 country.

Fouad T ChebibDivision of Nephrology and Hypertension, Mayo Clinic College of Medicine, Rochester, Minnesota, USA.
Marie C HoganDivision of Nephrology and Hypertension, Mayo Clinic College of Medicine, Rochester, Minnesota, USA.
Ziad M El-ZoghbyDivision of Nephrology and Hypertension, Mayo Clinic College of Medicine, Rochester, Minnesota, USA.
Maria V IrazabalDivision of Nephrology and Hypertension, Mayo Clinic College of Medicine, Rochester, Minnesota, USA.
Sarah R SenumDivision of Nephrology and Hypertension, Mayo Clinic College of Medicine, Rochester, Minnesota, USA.
Christina M HeyerDivision of Nephrology and Hypertension, Mayo Clinic College of Medicine, Rochester, Minnesota, USA.
Charles D MadsenDivision of Nephrology and Hypertension, Mayo Clinic College of Medicine, Rochester, Minnesota, USA.
Emilie Cornec-Le GallDivision of Nephrology and Hypertension, Mayo Clinic College of Medicine, Rochester, Minnesota, USA.
Atta BehfarDivision of Cardiovascular Diseases, Mayo Clinic College of Medicine, Rochester, Minnesota, USA.
Peter C HarrisDivision of Nephrology and Hypertension, Mayo Clinic College of Medicine, Rochester, Minnesota, USA.
Vicente E TorresDivision of Nephrology and Hypertension, Mayo Clinic College of Medicine, Rochester, Minnesota, USA.
Mayo Clinic · US

Funding

Pilot and FeasibilityP30DK090728 · NIDDK · MAYO CLINIC ROCHESTER · PI TORRES, VICENTE E · 2010 to 2019
$11.8M
ADPKD:Disease Spectrum &Genotype-Phenotype CorrelationsR01DK058816 · NIDDK · MAYO CLINIC ROCHESTER · PI Peter C. Harris · 2001 to 2026
$11.3M
RENIN ANGIOTENSIN SYSTEM IN THE PATHOGENESIS OF ADPKDR01DK044863 · NIDDK · MAYO CLINIC ROCHESTER · PI TORRES, VICENTE E · 1991 to 2019
$4.5M
NIDDK NIH HHS P30 DK090728NIDDK NIH HHS R01 DK044863NIDDK NIH HHS R01 DK058816
6 · The paper itself

Abstract

introductionMutations in

methodsClinical data were retrieved from medical records for patients with a coexisting diagnosis of ADPKD and cardiomyopathies evaluated at the Mayo Clinic (1984-2015).

resultsAmong the 58 of 667 patients with available echocardiography data, 39 (5.8%) had idiopathic dilated cardiomyopathy (IDCM), 17 (2.5%) had hypertrophic obstructive cardiomyopathy, and 2 (0.3%) had left ventricular noncompaction. Genetic data were available for 19, 8, and 2 cases of IDCM, hypertrophic obstructive cardiomyopathy, and left ventricular noncompaction, respectively. DISCUSSION: Coexistence of ADPKD and cardiomyopathy in our tertiary referral center cohort appears to be higher than expected by chance. We suggest that

Indexed as

ADPKDcardiomyopathieshypertrophic cardiomyopathyidiopathic dilated cardiomyopathyleft ventricular noncompactionpolycystic kidney

Identifiers

PMID29270497
PMCPMC5733883
OpenAlexW2564130259

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.