Evidence map›Paper›PMID 29270471›Full record

ArticleJournal of current ophthalmology2017

Comparison of macular choroidal thickness in patients with pseudoexfoliation syndrome to normal control subjects with enhanced depth SD-OCT imaging.

Sasan Moghimi, Mehdi Mazloumi, Mohammad Karim Johari, Masoud Aghsaie Fard, Rebecca Chen, Robert Weinreb, Kouros Nouri-Mahdavi

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Article in Journal of current ophthalmology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
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1 · What the graph read from it

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

7 authors.

Sasan MoghimiEye Research Center, Farabi Eye Hospital, Tehran University of Medical Sciences, Tehran, Iran.
Mehdi MazloumiEye Research Center, Farabi Eye Hospital, Tehran University of Medical Sciences, Tehran, Iran.
Mohammad Karim JohariEye Research Center, Farabi Eye Hospital, Tehran University of Medical Sciences, Tehran, Iran.
Masoud Aghsaie FardEye Research Center, Farabi Eye Hospital, Tehran University of Medical Sciences, Tehran, Iran.
Rebecca ChenKoret Vision Center, University of California, San Francisco Medical School, San Francisco, CA, USA.
Robert WeinrebHamilton Glaucoma Center, Department of Ophthalmology, University of California-San Diego, La Jolla, CA, USA.
Kouros Nouri-MahdaviStein Eye Institute, University of California, Los Angeles, CA, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo test the hypothesis that macular choroidal thickness is lower in patients with pseudoexfoliation syndrome (PXS) as compared to healthy control subjects.

methodsIn this cross-sectional, observational study, 38 non-glaucomatous PXS subjects and 37 healthy volunteers were enrolled in a tertiary care Glaucoma Clinic. The macular region was scanned with the enhanced depth imaging (EDI) protocol of a spectral domain optical coherence tomography (SD-OCT) device (Spectralis OCT, Heidelberg Engineering, Heidelberg, Germany). Macular choroidal thickness and volumes were compared in nine sectors of the Early Treatment Diabetic Retinopathy Study (ETDRS) layout profile across the central 3.45 mm zone after manual segmentation of the choroidal thickness. Linear mixed modeling was used to adjust for confounding variables.

resultsSix PXS eyes and 8 control eyes were excluded due to poor image quality leaving 32 PXS and 29 control eyes for final analyses. The average age and axial length of the PXS and control groups were 67.94 ± 7.30 vs 64.86 ± 7.04 and 22.91 ± 0.77 vs 23.24 ± 0.66 mm, respectively, (

conclusionsOur findings demonstrate that the choroid does not seem to be significantly altered in PXS eyes. Choroidal thickness changes need to be explored in PXS eyes with glaucoma.

Indexed as

ChoroidOptical coherence tomographyPseudoexfoliation

Identifiers

PMID29270471
PMCPMC5735235

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